The Department of Pathology Residency Program -
Molecular & Genomic Pathology

The molecular basis of most, if not all, human disease will ultimately be revealed by scientific and technical advances in the fields of molecular biology, genetics, and recombinant DNA technology. Modern molecular pathology practice in the Division of Molecular and Genomic Pathology is composed of two broad areas:
  • Molecular Oncology - solid tumor and hematolgic malignancies
  • Genetics
Residents rotating through this division are exposed to clinicians and scientists utilizing cutting-edge molecular techniques and pathology informatics technology to rapidly and accurately identify genetic sequences and alterations involved in neoplastic and non-neoplastic diseases. They will learn to analyze and interpret assays to diagnose inherited disorders and to accurately classify and guide therapy of neoplastic diseases. Techniques employed include Next Generation Sequencing (NGS) and Sanger sequencing methods as well as amplification technologies such as PCR, Allele specific PCR, Melt Curve analysis and SNaPshot assays among many others.

Exposure to the evolving practice of this subspecialty includes rotations through molecular anatomic pathology as well as the hematologic malignancy and genetics laboratories at the newly renovated Central Laboratory Building (CLB).

Research Emphasis

Major research emphases of faculty include the analysis of inflammation, regeneration, metabolism and neoplasia using experimental methods ranging from genome analysis, basic molecular biology to in vivo animal models.

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