Sara A. Monaghan, MD
Associate Professor of Pathology

Dr. Monaghan is a hematopathologist experienced in adult and pediatric bone marrow and lymphoid tissue pathology. She is the medical director of the Clinical Flow Cytometry Laboratory at UPMC Presbyterian. Her research interests focus on graduate medical education for hematopathology fellows, and the pathology and immunophenotyping by flow cytometry of hematolymphoid neoplasms. Her recent paper (Monaghan SA, et al. Am J Clin Pathol 2016;146:107) addresses the relationship between hematopathology fellows' performance on the twice-yearly in-service exam (ASCP FISHE) and performance on the American Board of Pathology (ABP) certifying exam for hematopathology. She is currently collaborating with the American Board of Pathology and the Society for Hematopathology to obtain data intended for use to promote harmonization of fellowship training requirements, the certifying exam and the real-life practice of hematopathology. Most of her publications related to pathology and immunophenotyping have focused on myeloid and plasma cell neoplasms.

Office Location:
Hill Building 3rd Floor, Rm #343
3477 Euler Way
Pittsburgh, PA 15213
Contact Information:
Office Telephone: 412-647-8504
Fax: 412-647-0374


  • MD - Mayo Medical School, Rochester, Minnesota, 1995

Clinical Expertise

  • Adult and pediatric bone marrow and lymphoid tissue pathology

Research Interests

  • Myeloproliferative neoplasms
  • Myelodysplastic syndromes
  • Plasma cell neoplasms
  • Flow cytometric immunophenotyping of malignancies (e.g. standardization and residual disease detection)
  • Graduate medical education


  • American Board of Pathology - Hematology, 2002
  • American Board of Pathology - Anatomic and Clinical Pathology, 2001


  • Flow cytometry analysis

Selected Publications

View Dr. Monaghan's publications on PubMed

  • Yao H, Ma Y, Hong Z, Zhao L, Monaghan SA, Hu MC, Huang LJ. Activating JAK2 mutants reveal cytokine receptor coupling differences that impact outcomes in myeloproliferative neoplasm. Leukemia. 2017 Jan 31. [Epub ahead of print] PMID: 28057939.
  • Koduru PR, Wilson K, Wen J, Garcia R, Patel S, Monaghan S. Cytogenetic and Cytogenomic Microarray Characterization of Chromothriptic-events in Chromosome 8 Affecting MOZ/NCOA2 (TIF2), FGFR1, RUNX1T1, and RUNX1 in a Pediatric Acute Myeloid Leukemia. J Pediatr Hematol Oncol. 2017;39:e227-32. PMID: 28085746.
  • Monaghan SA, Felgar RE, Kelly MA, Ali AM, Anastasi J, Bellara AP, Rinder HM, Sargent RL, Wagner J, Swerdlow SH, Johnson RL. Does Taking the Fellowship In-Service Hematopathology Examination and Performance Relate to Success on the American Board of Pathology Hematology Examination? Am J Clin Pathol. 2016 Jul;146(1):107-12. doi: 10.1093/ajcp/aqw085. PMID: 27357289.
  • Koduru P, Guruju N, Patel P, Wen J, Wilson K, Patel P, Monaghan S. A Unique Rearrangement of PDGFRα and ETV6 in a Patient with Acute Myeloid Leukemia with Myelodysplasia-Related Changes Progressed from Chronic Myelomonocytic Leukemia. Hematology and Leukemia. Hematol Leuk. 2016; 4:1.
  • Monaghan SA, Dai, L, Mapara MY, Normolle DP, Gollin SM, Lentzsch S. Longitudinal bone marrow evaluations for myelodysplasia in myeloma patients before and after treatment with lenalidomide. Leuk Lymphoma. 2013;54:1965-74. PMID: 23216269.
  • Monaghan SA, Surti U, Doty K, Craig FE. Altered Neutrophil Maturation Patterns that Limit Identification of Myelodysplastic Syndromes. Cytometry B Clin Cytom. 2012 Jul;82(4):217-28. PMID: 22431481.