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Research Interests:
Current interests include:
- Applied research on inherited diseases to include hereditary cancer syndromes. Primary projects address epidemiologic relationships and genotype-phenotype correlations in hereditary paraganglioma, hereditary breast and ovarian cancer, hereditary pancreatitis and malignant hyperthermia.
- Development and clinical application of assays for monitoring leukemia and lymphoma.
- Practice, policy and economic issues in clinical molecular diagnostics to include validation of genetic, oncology and infectious disease assays, the impact of intellectual property on provision of patient care, novel applications to improve diagnosis and monitoring of disease, and quality measures of laboratory performance
- Graduate medical education in molecular diagnostics and pathology to include improved approaches to education, evaluation and academic recruitment/retention.
Selected Publications:
Cherpes TL, Melan MA, Kant JA, Cosentino LA, Meyn LA, Hillier SL, Genital tract shedding of herpes simplex virus type 2 in women: effects of hormonal contraception, bacterial vaginosis, and vaginal group B Streptococcus colonization, Clin Infect Dis. 40:1422-1428, 2005.
Kant, J., Molecular Diagnostics in “The Role of Pathology and Laboratory Medicine in the Diagnosis of Cancer” M., Clinical Oncology-3rd ed., (eds. M. Abeloff, R. Armitage, J. Niederhuber, M. Kastan, W.G. McKenna, 3rd ed.), 320-328, 2004.
Kant, J.A. Techniques/Molecular (chapter 17), Yearbook of Pathology (2004), Mosby, Philadelphia, pp 285-296, 2004.
Tazelaar, J.T. and Kant, J.A., Genetic Testing for Pancreatitis, Expert Reviews of Molecular Diagnostics, 3: 799-809, 2003.
Monzon, F.A., Kant, J.A., Sanders, E., Bay, C., Gene symbol: UBE3A. Disease: Angelman syndrome, Hum. Genet., 113: 367, 2003.
Modugno, F.M., Moslehi, R., Ness, R.B., Nelson, D.B., Bell, S., Kant, J.A., Wheeler J.E., Wonderlick, A., Fishman, D., Karlan, B., Risch, H., Cramer, D.W., Dube, M-P., and Narod, S.A. Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutation carriers (United States), Cancer Causes and Control, 14: 439-446, 2003.
Kant, J., Molecular Biology of Inherited Diseases, chapter 8 in Clinical Laboratory Medicine, 2nd ed. (McClatchy, K., ed.), Lippincott Williams & Wilkins, 2002, pp. 163-174.
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