Parmjeet S. Randhawa, MD
Professor of Pathology
Dr. Randhawa is a member of the Division of Transplantation Pathology.
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Office Location: Division of Transplantation Pathology Department of Pathology UPMC-Montefiore, Room E-737 3459 5th Avenue Pittsburgh, PA 15213 |
Contact Information: Office Phone: 412-647-7646 Fax: 412-647-5237 Email: randhawapa@upmc.edu |
Research Interests
Dr. Randhawa's interests are renal transplantation, polyoma viral infections, and Epstein-Barr virus associated post-transplant lymphoproliferative disease (PTLD). A variety of clinicopathologic and molecular studies in these areas are currently in progress.Honors and Awards
- Appointed as International Society of Nephrology Educational Ambassador, June 2012.
- Elected Co-Chair, Transplant Diagnostics Community of Practice, American Society of Transplantation, May 2012.
- Co-Chair, Concurrent Session on Polyomavirus Infection in Kidney Transplantation: Diagnosis, Treatment and Outcomes. American Transplant Congress, June 2012.
- Member, Abstract Review Panel, The Transplant Society Meeting, Berlin, Germany, July 15-19, 2012
Selected Publications
View Dr. Randhawa's publications on PubMedKayler L, Mohanka R, Basu A, Shapiro R, Randhawa P. Single versus dual transplantation form donors with significant arteriosclerosis on preimplant biopsy. Clinical Transplantation, 23: 525-31, 2009.
Randhawa P, Viscidi R., Carter JJ, Galloway D, Culp TD, Huang Y, Ramaswami B, Christensen ND. Identification of Species-specific and Cross Reactive Epitopes in Human Polyomavirus Capsids Using Monoclonal antibodies. J Gen Virol, 2009 Mar; 90(3): 634-639.
Zeng, G., Bueno, M., Camachos, C.J., Ramaswami, B., Luo, C., and Randhawa, P. Validation of BKV Large T-antigen ATP-Binding Site as a Target for Drug Discovery. Antiviral Res 2009, 81: 184-187.
Gaurav Gupta, Ron Shapiro, Alin Girnita, Ibrahim Batal, Jerry McCauley, Amit Basu, Henkie Tan, Parmjeet Randhawa. Neutrophilic Tubulitis As A Marker For Urinary Tract Infection In Renal Allograft Biopsies With C4d Deposition. Transplantation, 2009, 87: 1013 -18.
Batal I, Chalasani G, Wu C, Shapiro R, Bastacky S, and Randhawa P. Deposition of Complement Product C4d in Anti-Glomerular Basement Membrane Glomerulonephritis. Am J Kidney Dis, 53(6):1098-101, 2009.
Luo C, Bueno M, Kant J, Martinson J, Randhawa P. Genotyping Schemes for Polyomavirus BK using Gene Specific Phylogenetic Trees and SNP Analysis. J Virol. 2009: 83(5): 2285-97.
Batal, I., Zainah, H., Stockhausen, S., Basu, A., Tan, H., Shapiro, R., Zeevi, A., Girnita, A., and Randhawa, P. The Significance of Renal C4d Deposits in Patients with BK Viruria, Viremia, and Nephropathy. Modern Pathology. 2009: 22: 1468-1476.
Batal, I., Franco, Z.M., Shapiro, R., Basu. A., Tan,H., Kayler, L., Zeevi, A., Morgan, C., and Randhawa, P. Clinicopathologic analysis of patients with BK viruria and rejection-like graft dysfunction. Human Pathology, 40: 1312-1319, 2009.
B. Ramaswami, Iulia Popescu, Camila Macedo, Marta Bueno, Diana Metes, Adriana Zeevi, Ron Shapiro, P. Randhawa. HLA-A01, -A03 and -A024 Binding Nanomeric Epitopes in Polyomavirus BK Large T-Antigen. Human Immunology, 70: 722-728, 2009.
Batal I, Domsic RT, Shafer A, Medsger TA Jr, Kiss LP, Randhawa P, Bastacky S: Renal biopsy findings predicting outcome in scleroderma renal crisis. Hum Pathol. Mar;40(3):332-40, 2009.
Hirsch HH, Randhawa P. BK virus in solid organ transplant recipients ( American Society of Transplantation Infectious Disease: Practice Guidelines for Polyomavirus BK). Am J Transplantation; 9 (Suppl 4): S132-S142, 2009.
Zeevi A, Lunz J, Shapiro R, Randhawa P, Mazariegos G, Webber S, Girnita A. The Emerging Role of Donor-Specific Anti-HLA Antibody Determination for Clinical Management after Solid Organ Transplantation. Hum Immunol, 70(8):645-50, 2009.
Shapiro R, Basu A, Zeevi A, Lunz J, Mapara M, Randhawa P, Morgan C, Tan HP, Sharma V. Bortezomib rescue in refractory acute humoral rejection—report of a case. Clin Transpl: 431-2, 2009.
Tan HP, Donaldson J, Basu A, Unruh M, Randhawa P, Sharma V, Morgan C, McCauley J, Wu C, Shah N, Zeevi A, Shapiro R. Two hundred living donor kidney transplantations under alemtuzumab induction and tacrolimus monotherapy: 3-year follow-up. Am J Transplant. Feb;9(2):355-66, 2009.
Shapiro R, Basu A, Tan HP, Morgan C, Sharma V, Blisard D, Randhawa PS, Dvorchik I, McCauley J, Ellis D, Marsh JW, Webber S, Kurland G, McCurry KR, Abu-Elmagd K, Mazariegos G, Starzl TE. Kidney after nonrenal transplantation-the impact of alemtuzumab induction. Transplantation. Sep 27; 88(6):799-802, 2009.
Randhawa P, Schonder K, Shapiro R, Farasati N, Huang C. Polyomavirus BK Neutralizing Activity in Human Immunoglobulin Preparations. Transplantation. Jun 27;89(12):1462-5, 2010.
Randhawa PS, Farasati NA, Huang Y, Mapara MY, Shapiro R. Viral drug sensitivity testing using quantitative PCR: effect of tyrosine kinase inhibitors on polyomavirus BK replication. Am J Clin Pathol, 134(6): 916-920, 2010.
Sis B, Mengel M, Haas M, Colvin R, Halloran P, Racusen L, Solez K, Broecker V, Baldwin III W, Bracamonte E, Cosio F, Demetris AJ, Drachenberg C, Einecke G, Gloor J, Glotz D, Kraus E, Legendre C, Liapis H, Mannon R, Matas A, Nankivell B, Nickeleit V, Papadimitriou J, Randhawa P, Regele H, Renaudin K, Rodreguez ER, Seron D, Seshan S, Stegall M, Suthanthiran M, Wasowska B, Zachary A, Zeevi A. Banff ’09 Meeting Report: Antibody Mediated Graft Deterioration and Implementation of Banff Working Groups. Am J Transplant, 10: 464-471, 2010.
Batal I, Zeevi A, Lunz JG 3rd, Aggarwal N, Shapiro R, Randhawa P, Girnita A. Antihuman leukocyte antigen-specific antibody strength determined by complement-dependent or solid-phase assays can predict positive donor-specific crossmatches. Arch Pathol Lab Med. Oct;134(10):1534-40. 2010.
Batal I, Lunz JG 3rd, Aggarwal N, Zeevi A, Sasatomi E, Basu A, Tan H. Shapiro R, Randhawa P. A Batal I, Lunz JG, Aggarwal N, Zeevi A, Sasatomi E, Basu A, Tan H, Shapiro R, Randhawa P. A critical appraisal of methods to grade transplant glomerulitis in renal allograft biopsies. Am J Transplant 10: 2442-2452, 2010.
Momper JD, Zhang S, Randhawa PS, Shapiro R, Schonder KS, Venkataramanan R. Determination of cidofovir in human plasma after low dose drug administration using high-performance liquid chromatography tandem mass spectrometry. J Pharm Biomed Anal. Dec 1;53(4):1015-21, 2010.
Trivedi H, Nachmany I, Randhawa P, Humar A, Shapiro R, Basu A. Image of the month—quiz case. Angiosarcoma. Arch Surg. Dec; 145(12):1209, 1210. 2010.
Shapiro R, Lunz J, Zeevi A, Basu A, Mapara M, Randhawa P, Tan HP, Sharma V, Humar A. 1.7 year follow up after Bortezomib therapy for refractory antibody mediated rejection. Clin Transplant, 405-407, 2010.
Cajaiba M, Parks WT, Fuhrer K, and Randhawa P. Evaluation of human polyomavirus BK as a potential cause of villitis of unknown etiology and spontaneous abortion. J Med Virol, 2011 Jun;83(6):1031-1033.
Cheng X, Bohl DL, Storch GA, Ryschkewitsch C, Gaudreault-Keener M, Major EO, Randhawa P, Brennan DC. Potential Inhibitory Interactions between BK and JC Virus in Kidney Transplant Patients. J Am Soc Nephrol, 22: 825-831, 2011
Ramaswami B, Popescu I, Macedo C, Luo C, Shapiro R, Metes D, Chalasani G, Randhawa P. Polyomavirus BK Large T-antigen derived peptide elicits aHLA-DR promiscuous and polyfunctional CD4+ T-cell response. Clinical Vaccine Immunology, 18: 815-824, 2011.
Luo C, Kant J, Shapiro R, Tan H, Basu A, Randhawa P. The Impact of Genomic Sequence Variability on Quantitative PCR Assays for Diagnosis of Polyomavirus BK Infection. J Clin Microbiol, 49:3072-76, 2011.
Ashokkumar C, Shapiro R, Tan H, Elinoff B, Fedorek S, Sun Q, Higgs BW, Randhawa P, Humar A, Sindhi R. Allospecific CD154+ T-cytotoxic memory cells identify recipients experiencing acute cellular rejection after renal transplantation. Transplantation, 92: 433-438, 2011.
Drachenberg C, Haririan A, Mittalhenkle A, Nankivell B, Bromberg J, Kim DU, Campani D, Klassen D, Sutherland D, Cantarovich D, Kraus E, Bracamonte E, Honsova E, Farris AB, Finn R, Lower F, Rennke H, Bajema I, Brujin J, Olson JL, Chapman J, Papadimitriou JC, Odorico J, Torrealba J, Goldberg J, Renaudin K, Gaber L, Arend L, Racusen L Voska L, Troxell M, Samaniego M, Revelo P, Ruiz P, Munivenkatappa R, Gruessner R, Randhawa P, Stratta R, Shapiro R, Iskandar S, Bartlett S, Paraskevas S, Seshan SV. Guidelines for the diagnosis of antibody mediated rejection in pancreas allografts-Updated BANFF Grading Schema. Am J Transpant, 11: 1792-1802, 2011.
Batal I, Azzi J, El-Haddad N, Riella LV, Lunz III JG, Zeevi A, Sasatomi E, Basu A, Tan H, Shapiro R, and Randhawa P. Immunohistochemical Markers of Tissue Injury in Biopsies with Transplant Glomerulitis. Human Pathology, 43:69-80, 2012.
Luo C, Hirsch H, Kant J, Randhawa P. VP-1 Quasispecies in Human Infection with Polyomavirus BK. J Med Virol, 84: 152-61, 2012.
Lunz J, Ruppert K, Cajaiba M, Isse K, Minervini M, Nalesnik, M, Randhawa P, Rubin E, Sasatomi E, Fontes P, Humar A, Zeevi A, Demetris A. Re-examination of the lymphocytic cross match in liver transplantation: can C4d stains help in monitoring? Am J Transplant 12: 171-182, 2012