Hospital Course -- Intracranial Hemorrhage and Seizure Activity


Blood and urine cultures performed on admission were negative for organisms. However, the patient was given an empiric course of gentamicin and ampicillin because of the high clinical suspicion for sepsis and the inability to perform a lumbar puncture due to increased intracranial pressure. In addition to the slowly resolving intracranial hemorrhage, the child had gross hematuria and heme-positive stools. The patient received daily injections of vitamin K and 10 - 15 ml/kg of fresh frozen plasma every 6-8 hours with only partial correction of his PT. Additional coagulation studies revealed a Factor II activity of 0.81 U/ml (normal range 0.7 - 1.4) and a Factor VII activity of 0.07 U/ml (normal range 0.6 - 1.6) while receiving fresh frozen plasma.



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