Douglas J. Hartman, MD
Associate Professor of Pathology

Dr. Hartman is a member of the Division of Anatomic Pathology. He is also the Associate Director of the Pathology Informatics Division and Director of Image Analysis Laboratory.

Office Location:
Rm. A610
Presbyterian University Hospital
200 Lothrop Street
Pittsburgh, PA 15213
Contact Information:
Office Telephone: 412-864-3552


  • BA - 1999, Xavier University
  • MD - 2004, University of Cincinnati College of Medicine
  • AP/CP Pathology Residency - 2008, University Hospitals of Cleveland/Case Western Reserve University
  • Pathology Fellowship - 2009, Gastrointestinal Pathology, University of Pittsburgh Medical Center

Clinical Expertise

Dr. Hartman is an Academic Surgical Pathologist with a subspecialty interest and focus in Gastrointestinal and Pancreatic pathology. He also consults on surgical pathology cases involving the luminal GI tract and pancreas.

Research Interests

Dr. Hartman's current primary research interests are in the field of idiopathic inflammatory bowel disease: underlying mechanisms, molecular pathogenesis of dysplasia development; associated disorders; and post-surgical complications. Other areas of research include peritoneal mesothelioma, molecular abnormalities in colon cancer, and the application of pathology informatics. Dr. Hartman is a co-investigator on institutional grants. Dr. Hartman is actively involved in research for digital pathology, image analysis and artificial intelligence/machine learning.


Diplomate of the American Board of Pathology in combined Anatomic Pathology and Clinical Pathology
Diplomate of the American Board of Pathology in Clinical Informatics


Surgical Pathologist with subspecialty interest and training in gastrointestinal / pancreatic pathology

Professional Affliations

  • United States and Canadian Association of Pathology 2008-Present
  • College of American Pathologists 2008-Present
  • American Society for Clinical Pathology 2008-Present

Major Lectureships

2014 United States and Canadian Pathology (USCAP) Practice Changers Talk "Integration of Smartphone Technology into the Practice of Anatomic Pathology"

Selected Publications

View Dr. Hartman's publications on PubMed

  • Hartman DJ. Mobile Technologies for the Surgical Pathologist. Surg Pathol Clin, 2015 Jun; 8(2): 233-238. PMID: 26065797.
  • Hartman DJ. Enhancing and Customizing Laboratory Information Systems to Improve/Enhance Pathologist Workflow. Surg Pathol Clin, 2015 Jun; 8(2): 137-143. PMID: 26065788.
  • Grandhi R, Hunnicutt CT, Harrison G, Zwagerman NT, Snyderman CH, Gardner PA, Hartman DJ, Horowitz M. Comparing Angiographic and Histologic Penetrance After Preoperative Tumor Embolization with Onyx: Is There a Way to Predict Intraoperative Blood Loss? Journal of Neurological Surgery-A Cent Eur Neurosurg, 2015 Jan 16 [Epub ahead of print]. PMID: 25594815.
  • Tang H, Singh S, Partyka K, Kletter D, Hsueh P, Yadav J, Ensink E, Bern M, Hostetter G, Hartman D, Huang Y, Brand RE, Haab BB. Glycan Motif Profiling Reveals Plasma Sialyl-Lewis X Elevations in Pancreatic Cancers that are Negative for Sialyl-Lewis A. Mol Cell Proteomics, 2015 May; 14(5): 1323-33. PMID: 25733690.
  • Malik S, Raina A, Hartman DJ. Immunoglobulin G4-Related Pseudotumor Presenting as Metastatic Colon Cancer. Clin Gastro and Hepatol, 2015 Jan; 13(1): e1-2. PMID: PMID: 25220937.
  • Deberry JJ, Bielefeldt K, Davis BM, Szigethy EM, Hartman DJ, Coates MD. Abdominal Pain and the Neurotrophic System in Ulcerative Colitis. Inflamm Bowel Dis, 2014 Dec; 20(12): 2330-9. PMID: 25358061.
  • Roy SR, Pantanowitz L, Amin M, Seethala RR, Ishtiaque A, Yousem SA, Cucorano I, Parwani AV, Hartman DJ. Smartphone Adapters in Digital Photomicrography. J Pathol Inform, 2014:5:24. PMID: 25191623.
  • Reguiero M, Hartman DJ, Schraut W, Watson A, Cross R, Williams E, Herfarth H, Siegel CA, Oikonomu I, Tublin M, Binion DG. The Inflammatory Bowel Disease Live Interinstitutional and Interdisciplinary Videoconference Education (IBD LIVE) series. Inflamm Bowel Dis, 2014 Oct; 20(10): 1687-95. PMID: 25167213.
  • Iskander H, Hartman DJ, Schraut W, Herfarth H, Siegel CA, Williams E, Schwartz M. IBD LIVE Case Series Case 1: Smoking, a Controversial but Effective Treatment for Ulcerative Colitis. Inflamm Bowel Dis, 2014 Oct; 20(10): 1696-701. PMID: 25167214.
  • Hartman DJ, Binion DG, Bahary N, Sun W, Schraut W, Reguiero M, Nikiforova MN, Pai RK. Isocitrate Dehydrogenase-1 is Mutated in Inflammatory Bowel Disease-Associated Intestinal Adenocarcinoma with Low-Grade Tubuloglandular Histology But Not in Sporadic Intestinal Adenocarcinoma. Am J Surg Pathol 2014 Aug;38(8):1147-56. PMID: 25029120.
  • Hartman DJ, Yadav D and Binion DG. Reply: Tissue IgG4-positive plasma cells in inflammatory bowel disease: a study of 88 treatment-na´ve biopsies of inflammatory bowel disease. Mod Pathol, 2014 Jun;27(6):916. PMID: 24881558.
  • Hartman DJ, Parwani AV, Cable B, Cucoranu IC, McHugh JS, Kolowitz BJ, Yousem SA, Palat V, Von Reden A, Sloka S, Romero Lauro G, Ahmed I, Pantanowitz L. Pocket Pathologist: A Mobile Application for Rapid Diagnostic Surgical Pathology Consultation. J Pathol Inform 2014 Mar 28;5:10. PMID: 24843822
  • Hartman DJ, Krasinskas AM, Uttam S, Bista RK, Staton K, Sumera R, Slivka AS, Brand RE, Liu Y. Assessment of nuclear nano-morphology marker to improve the detection of malignancy from bile duct biopsies. Am J Clin Pathol. 2014 Jun;141(6):884-91. PMID: 24838334.
  • Cheng S, Clancy C, Hartman DJ, Hao B, Nguyen HM. Candida Glabrata Intra-abdominal Candidiasis is Characterized by Persistence within the Peritoneal Cavity and Abscesses. Infect Immun, 2014 Jul;82(7):3015-3022. Epub 2014 May 5. PMID: 24799629.
  • Davison JM, Hartman DJ, Singhi AD, Choudry HA, Ahrendt SA, Zureikat AH, Ramalingam L, Nikiforova M, Pai RK. Loss of SMAD4 Protein Expression is Associated with High Tumor Grade and Poor Prognosis in Disseminated Appendiceal Mucinous Neoplasms. Am J Surg Pathol. 2014 May; 38(5):583-92. PMID: 24618609.
  • Gurvinder B, Hartman DJ, Haight JB,Gibson M. A rare case of malignant glomus tumor involving the esophagus. Case Rep Oncol Med. 2013; 2013:287078. Epub 2013 Dec 17. PMID: 24455358
  • Stopczynski RE, Normolle D, Hartman DJ, Ying H, Deberry JJ, Bielefeldt K, Rhim AD, Depinho RA, Albers KM, Davis BM. Neuroplastic changes occur early in the development of pancreatic ductal adenocarcinoma. Cancer Res. 2014 Mar 15; 74(6):1718-27. doi: 10.1158/0008-5472. CAN-13-2050. Epub 2014 Jan 21. PMID: 24448244
  • Pai RK, Hartman DJ, Gonzalo DH, Lai KK, Downs-Kelly E, Goldblum JR, Liu X, Patil DT, Bennett AE, Plesec TP, Kuan SF, Nikiforova MN, Shadrach B, Pai RK. Serrated Lesions of the Appendix Frequently Harbor KRAS Mutations and Not BRAF Mutations Indicating a Distinctly Different Serrated Neoplastic Pathway in the Appendix. Human Pathol. 2014 Feb;45(2):227-35. Epub 2013 Oct 30. PMID: 24439221.
  • Hartman DJ and Chiosea SI. Colorectal carcinomas, KRAS p.G13D mutant specific-allelic imbalance, and anti-epidermal growth factor receptor therapy. Cancer. 2013 Dec 15; 119 (24):4366. Epub 2013 Sep 24. PMID: 24113994.
  • Hartman DJ, Brand RE, Hu H, Bahary N, Dudley B, Chiosea SI, Nikiforova MN, Pai RK. Lynch Syndrome-Associated Carcinoma: Frequent Involvement of the Left Colon and Rectum and Late-Onset Presentation Supports a Universal Screening Approach. Hum Pathol. 2013 Nov; 44(11):2518-28 Epub 2013 Sep 10. PMID: 24034859.
  • Hartman DJ, Kelly SM, Wiehagen LT, Yousem SA. Tissue Adequacy for Ancillary Studies Beyond Frozen Section: A Potential Method for Improving Diagnostic and Therapeutic Results. Int J Surg Pathol. 2013 Dec;21(6):583-6. Epub 2013 Sep 2. PMID: 23999115.
  • Criscimanna A, Duan D, Rhodes JA, Fendrich V, Wickline ED, Hartman DJ, Monga SP, Lotze M, Gittes GK, Fong GH, Esni F. PanIN-specific regulation of Wnt signaling by HIF2. Cancer Res. 2013 Aug 1;73(15):4781-4790. Epub 2013 Jun 7
  • Hartman D, Krasinskas AM, Sasatomi E. Caveat Emptor: submitting the entire gallbladder in cases of dysplasia is not justified. Am J Clin Pathol. 2013 Jun; 139(6):830
  • Hartman DJ, Nikiforova MN, Chang DT, Chu E, Bahary N, Brand RE, Zureikat A, Zeh HJ, Pingpank J, Bartlett D, Pai RK. Signet Ring Cell Colorectal Carcinoma: A Distinct Subset of Mucin-Poor Microsatellite Stable Signet Ring Carcinoma Associated with Dismal Prognosis. Am J Surg Pathol, 2013 Jul; 37(7): 969-77.
  • Mitchell KM, Kluger H, Snzol M, Hartman DJ. Ipilimumab induced perforating colitis. J Clin Gastroenterol, Epub 2013 Apr 29.
  • Raina A, Yadav D, Regueiro M, Krasinskas AM, Saul MI, Sapienza DA, Binion DG and Hartman DJ. Mucosal IgG4 Cell Infiltration in Ulcerative Colitis is Linked to Disease Activity and Primary Sclerosing Cholangitis. Inflamm Bowel Dis 2013 May; 19(6): 1232-7
  • Uttam S, Bista RK, Staton K, Alexandrov A, Choi S, Bakkenist CJ, Hartman DJ, Brand RE and Liu Y. Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and gene expression. Biomedical Optics Express, 2013 Apr 1;4(4):596-613. doi: 10.1364/BOE.4.000596. Epub 2013 Mar 22