Qingyong Xu, PhD, ABHI (D)
Assistant Professor of Pathology


Dr. Xu is Associate Director of the Tissue Typing Laboratory that provides 24 hr/ 7 day service to the solid organ and bone marrow transplant program at UPMC, VA and Children's.

Office Location:
3477 Euler Way
Room 4032
Pittsburgh, PA 15213

 Contact Information:
Office Phone: 412-647-0462
Email: xuq5@upmc.edu

Education

  • BA, Biochemistry - 1998, Yantai University, Yantai, China
  • MS, Developmental Biology - 2001, Chinese Academy of Sciences, Beijing, China
  • PhD, Comparative Biomedical Science - 2007, University of Wisconsin - Madison, Madison, WI

Clinical Expertise

Dr. Xu has more than 10-year experience in clinical histocompatibility and immunogenetics, and has been directors of ASHI-certified HLA labs in Canada. He was known for his expertise in new lab setup, test utilization and quality improvement. Currently Dr. Xu is the Associate Director of Histocompatibility (Tissue Typing) Lab at UPMC. The lab provides comprehensive histocompatibility services to multiple solid organ and hematopoietic stem cell transplant programs in UPMC system, VA hospital and Western Virginia. Dr. Xu is an expert in test interpretation, immunological risk assessment for organ transplantation and hematopoietic stem cell transplantation. Specifically, Dr. Xu provides consultation to clinicians regarding patient/donor selection and therapeutic regimens before transplantation, diagnosing and treatment of rejection after transplantation.

Research Interests

  1. Auto antibodies in organ transplantation, especially in liver transplantation. Previously, we had reported that pre-formed Angiotensin II Type I Receptor agonistic autoantibodies (AT1R-AA) are associated with poor allograft survival in liver re-transplantation (Xu, et al, AJT, 2019). Currently we are studying other autoantibodies in liver, lung and heart transplantations.
  2. Novel approaches to monitor allo-specific humoral and cellular responses before and post organ transplantation for better clinical decision making.

Selected Publications

  1. Jennifer McCaughan, Qingyong Xu, Kathryn Tinckam. Detecting DSA: the importance of sorting the wheat from the chaff. HepatoBiliary Surgery and Nutrition, 2019 Jun 10; 8 (1): 37-52. Senior Responsible Author
  2. Qingyong Xu, Brad Shrum, Steve Leckie, Anton Skaro and Vivian C McAlister. The impact of donor specific alloantibodies on long-term outcomes of liver re-transplantation. HepatoBiliary Surgery and Nutrition, 2019 Jun 9; 8 (3): 246-252. Principal Author
  3. Qingyong Xu, Andrew A. House, Steve Leckie, Lakshman Gunaratnam, Patrick P. Luke, Anthony M. Jevnikar. Patients With Immunological Diseases Or On Peritoneal Dialysis Are Prone To False Positive Flow Cytometry Cross Match. Human Immunology, 2019 Jun 10. Principal & Responsible Author
  4. Qingyong Xu, Vivian C. McAlister, Steve Leckie, Andrew A. House, Anton Skaro, Paul Marotta,. Angiotensin II Type I Receptor Agonistic Autoantibodies are Associated with Poor Allograft Survival in Liver Re-transplantation. American Journal Transplantation, 2019 Aug 16. doi: 10.1111/ajt.15571. Principal & Responsible Author