Case 1023 -- Gastric Biopsy from Man in His 40's - Can AI Make the Diagnosis?

Contributed by Robin Dietz, MD and Liron Pantanowitz, MD


A man in his mid 40s underwent esophagogastroduodenoscopy (EGD) after several months of vague abdominal pain. Random biopsies of his gastric mucosa were taken. A representative field of the antral gastric biopsy (H&E stain, high magnification) is shown in the image below (Figure 1).

Figure 1. Photomicrograph showing gastric antrum mucosa without inflammatory cells.

No obvious Helicobacter pylori (HP) organisms were identified on the H&E stain. Further testing including immunohistochemistry to rule out HP was therefore considered.


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