Clinical Virology Laboratory -
Research in the UPMC Clinical Virology Laboratory

The Clinical Virology Laboratory is committed to conducting extensive research on topics that relate to improving our understanding of clinical virology, and optimally caring for patients with viral illnesses.

Since UPMC Presbyterian University Hospital is one of the premier organ transplant centers in the United States, detecting viruses such as CMV that are associated with mortality in organ transplant recipients enables appropriate treatment strategies to be devised ahead of transplantation.

To this end, we have a long record of clinical research in collaboration with UPMC clinicians, the molecular diagnostics and biopharmaceutical industries, as well as colleagues at other institutions.

Current research interests include:

  • CDC influenza vaccine efficacy study
  • Assessment of herpesvirus infections in organ transplant recipients
  • One of the longest-running NIH studies of the natural history of HIV/AIDS
  • NIH AIDS clinical trials
  • Dendritic cell therapy in AIDS

As Chairman and Professor of the Department of Infectious diseases and Microbiology at the University of Pittsburgh Graduate School of Public Health, Dr. Rinaldo also directs an extensive, complementary basic research program on the natural history and immunopathogenesis of HIV (human immunodeficiency virus type-1) and HHV-8 (human herpes virus 8; Kaposi's sarcoma associated herpes virus).


Charles R. Rinaldo, Jr., PhD