Somak Roy, MD
Assistant Professor of Pathology

Dr. Roy is a member of the Division of Molecular & Genomic Pathology and Assistant Director of the MGP Laboratory.

Office Information:
Clinical Lab Building
3477 Euler Way
Room 7028
Pittsburgh, PA 15213
Contact Information:
Telephone: 412-864-6190

Research Interests

Dr. Roy's research is focused on understanding mechanisms of urothelial carcinogenesis and metastasis using next generation sequencing and microarray technologies and development of biomedical informatics solutions for optimizing clinical laboratory operations and quality management.

Selected Publications

View Dr. Roy's publications on PubMed

  • Roy S, LaFramboise WA, Nikiforov YE, Nikiforova MN, Routbort MJ, Pfeifer J, Nagarajan R, Carter AB, Pantanowitz L. Next-Generation Sequencing Informatics. Arch Pathol Lab Med. 2016 Feb 22. [Epub ahead of print]
  • Roy S. Molecular Pathology Informatics. Clin Lab Med. 2016 Mar;36(1):57-66.
  • Roy S, Pfeifer JD, Laframboise WA, Pantanowitz L. Molecular telepathology: Progress and potential of exchanging molecular data. Accepted for publication in Expert Rev Mol Diagn March 2016.
  • Nikiforova MN, Wald AI, Melan MA, Roy S, Zhong S, Hamilton RL, Lieberman FS, Drappatz J, Amankulor NM, Pollack IF, Nikiforov YE, Horbinski C. Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors. Neuro Oncol. 2016 Mar;18(3):379-87.
  • Cancer Genome Atlas Research Network. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. N Engl J Med. 2016 Jan 14;374(2):135-45.
  • Pradhan D, Roy S, Quiroga-Garza G, Cieply K, Mahaffey AL, Bastacky S, Dhir R, Parwani AV. Validation and utilization of a TFE3 break-apart FISH assay for Xp11.2 translocation renal cell carcinoma and alveolar soft part sarcoma. Diagn Pathol. 2015 Sep 29;10:179.
  • Roy S, Durso MB, Wald A, Nikiforov YE, Nikiforova MN. SeqReporter: Automating next generation sequencing result interpretation and reporting workflow in a clinical laboratory. J Mol Diagn. 2014 Jan;16(1):11-22 (Featured article of journal's Jan 2014 issue). PMID: 24220144.
  • Roy S, Parwani AV, Dhir R, Yousem SA, Kelly SM, Pantanowitz L. Frozen section diagnosis: Is there discordance between what pathologists say and what surgeons hear? Am J Clin Pathol. 2013;140:363-9. PMID: 23955455.
  • Nikiforova MN, Wald A, Roy S, Durso MB, Nikiforov YE. Targeted next-generation sequencing panel (ThyroSeq) for detection of mutations in thyroid cancer. J Clin Endocrinol Metab. 2013;98:E1852-60. PMID: 23979959.
  • Roy S, Amin M, Seethala RR, Ishtiaque A; Yousem SA, Parwani AV, Cucoranu I, Pantanowitz L, Hartman DJ. Smartphone Adapters for Photomicrograph Acquisition. Accepted for publication in J Pathol Inform March 2014.
  • Roy S, Parwani AV, Pantanowitz L. Bioinformatics. In: Practical Informatics for Cytology (Springer). Eds. Dr A.V. Parwani, Dr L. Pantanowitz. 2014
  • Roy S, Parwani AV, Pantanowitz L. Research informatics. In: Practical Informatics for Cytology (Springer). Eds. Dr A.V. Parwani, Dr L. Pantanowitz. 2014
  • Jain S, Roy S, Amin M, Acquafondata M, Yin M, Laframboise W, Bastacky S, Pantanowitz L, Dhir R, Parwani A. Amylase α-1A (AMY1A): A Novel Immunohistochemical Marker to Differentiate Chromophobe Renal Cell Carcinoma From Benign Oncocytoma. Am J Surg Pathol. 2013;37:1824-30. PMID: 24225843.
  • Roy S, Smith MA, Cieply KM, Acquafondata MB, Parwani AV. Primary bladder adenocarcinoma versus metastatic colorectal adenocarcinoma: a persisting diagnostic challenge. Diagn Pathol. 2012;7:151. PMID: 23121893.
  • Roy S, Hooda S, Huang GJ, Pantanowitz L, Parwani AV. A Novel Case of Concurrent Renal Tumors: Chromophobe Renal Cell Carcinoma and Carcinoid Tumor of the Kidney With Brief Review of Renal Neuroendocrine Tumors. Int J Surg Pathol. 2012 Mar 27. PMID: 22456871.
  • Roy S, Hooda S, Parwani AV. Idiopathic granulomatous orchitis. Pathol Res Pract. 2011;207:275-8. PMID: 21458170.