Christine Garcia Roth, MD
Associate Professor of Pathology

Dr. Roth is a member of the Division of Hematopathology and Co- Medical Director, UPMC Clinical Flow Cytometry Laboratory. Director, Hematopathology Core Residency Rotation.

Office Location:
Suite G300
UPMC-PUH
200 Lothrop Street
Pittsburgh, PA 15213
Contact Information:
Office Telephone: 412-647-0382
Fax: 412-647-0374
Email: garciac@upmc.edu

Education

  • MD - Baylor College of Medicine, 2001

Certifications

  • Diplomate, American Board of Pathology, Anatomic and Clinical Pathology, 2006
  • Diplomate, American Board of Pathology, Specialty Certification in Hematology 2007

Clinical Expertise

Hematopathology, including bone marrow and lymph node pathology, and application of flow cytometric, immunohistochemical, cytogenetic, and molecular studies in clinical diagnosis

Research Expertise

Pathobiology and classification of hematopoietic processes, including myeloid and lymphoid malignancies, and applications of virtual microscopy to hematopathology education

Honors and Awards

Provost’s Advisory Council on Instructional Excellence (ACIE) Innovation in Education Award - 2012

Selected Publications

View Dr. Roth's publications on PubMed

Roth CG, Garner K, Ten Eyck S, Boyiadzis M, Kane LP, Craig FE. TIM3 expression on normal and leukemic myeloblasts. Cytometry Part B 2013 [in press]

Rollins-Raval MA, Marafioti T, Swerdlow SH, Roth CG. The number and growth pattern of plasmacytoid dendritic cells vary in different types of reactive lymph nodes: an immunohistochemical study. Human Pathology. [in press]

Rollins-Raval MA, Pillai R, Warita K, Mitsuhashi-Warita T, Mehta R, Djokic M, Kant JA, Roth CG. CD123 immunohistochemical expression in acute myeloid leukemia is associated with underlying FLT3-ITD and NPM1 mutations. Applied Immunohistochemistry and Molecular Morphology. 2012 Aug 20 [Epub ahead of print]

Roth CG, Reichard KK. Subtle bone marrow involvement by large B cell lymphoma with pronormoblast-like morphology and prominent but not exclusive sinusoidal distribution. American Journal of Blood Research. 2012; 2(2): 113-8.

Roth CG, Dangott BJ, Harper T, Duboy J, Craig FE, Parwani A. Construction and implementation of a comprehensive hematopathology virtual teaching set. Journal of Hematopathology [in press]

Rollins-Raval MA, Roth CG. The value of CD14, CD123, CD33, MPO, and CD68R immunohistochemical stains in the diagnosis of acute and chronic myelomonocytic leukaemias. Histopathology. 2012; 60(6): 933-42.

Rollins-Raval MA, Fuhrer K, Marafioti T, Roth CG. ALDH, Carbonic anhydrase 1, and CD2AP: Novel, diagnostically useful immunohistochemical markers to identify erythroid precursors in bone marrow biopsies. American Journal of Clinical Pathology. 2012; 137(1) 30-8.

Rollins-Raval MA, Felgar F, Krasinskas AM, Roth CG. Significantly increased IgG4/IgG ratios may be rarely seen in lymph nodes of patients without IgG4-related sclerosing disease. International Journal of Surgical Pathology. 2012; 20(1): 47-53.

Roth CG, Contis LC, Gupta S, Agha M, Safyan E. De novo acute myeloid leukemia with Philadelphia chromosome (BCR-ABL) and inversion 16 (CBFB-MYH11): Report of two cases and review of the literature. Leukemia Lymphoma 2011; 52 (3): 531 -5.

Hasserjian RP, Zuo Z, Garcia C, Tang G, Kasyan A, Luthra R, Abruzzo LV, Kantarjian HM, Medeiros LJ, Wang SA. Acute erythroid leukemia: A reassessment using criteria refined in the 2008 WHO classification. Blood 2010; 115(10) 1985 – 92.

Garcia CF, Hunt KE, Kang H, Babb A, Gale JM, Vasef MA, Reichard KK. Most morphologic features do not reliably predict underlying FISH genetics or immunoglobulin heavy chain variable region somatic mutational status. Appl Immun Molec Morph. 2010; 18(2): 119 – 27.