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Research Interests:
Dr. Yousem is a Professor of Pathology at the University of Pittsburgh Medical Center. He has a special interest in inflammatory lung disease and lung transplantation, which originated during his residency at Stanford University Medical Center under the guidance of Thomas V. Colby, M.D. and the late Charles B. Carrington, M.D. Following a surgical pathology fellowship and a junior staff position at Stanford, Dr.Yousem spent two years in the Division of Pulmonary and Mediastinal Pathology at the Armed Forces Institute of Pathology. In 1987 he joined the Pathology Department at the University of Pittsburgh Medical Center, and he now marries his responsibilities in lung transplantation with responsibilities as Director of Anatomic Pathology. He has a primary interest in interstitial and small airway inflammatory processes of the lung, and the histopathologic alterations of acute rejection and bronchiolitis obliterans in lung allografts. These interests have culminated in a large body of scientific publications and numerous invited lectureships and courses in national and international societies and forums.
Selected Publications:
View Dr. Yousem's publications on PubMed.
Dacic S, Ionescu DN, Finkelstein S, Yousem SA. Patterns of allelic loss of synchronous adenocarcinomas of the lung. Am J Surg Pathol. 2005, 29:897-902.
Yousem SA , Dacic S. Pulmonary lymphohistiocytic reactions temporally related to etanercept therapy. Mod Pathol. 18:651-5, 2005.
Dacic S, Finkelstein SD, Yousem SA. Clonal selection of adenocarcinoma of the lung as determined by loss of heterozygosity. Experimental and Molecular Pathology 78:135-9, 2005.
Girnita AL, Duquesnoy R, Yousem SA, Iacono AT, Corcoran TE, Buzoianu M, Johnson B, Spichty KJ, Dauber JH, Burckart G, Griffith BP, McCurry KR, Zeevi A. HLA-specific antibodies are risk factors for lymphocytic bronchiolitis and chronic lung allograft dysfunction. Am J Transplant 5:131-8, 2005.
Ionescu D, Sasatomi E, Aldeeb D, Omalu B, Finkelstein S, Swalsky P, Yousem S. Pulmonary meningothelial-like nodules: a genotypic comparison with meningiomas. Am J Surg Pathol 28:207-14, 2004.
Sasatomi E, Johnson LR, Aldeeb DN, Lomago DM, Thompson Jr JW, Swalsky PA, Luketich JD, Fernando HC, Finkelstein SD, Yousem SA. Genetic profile of cumulative mutational damage associated with early pulmonary adenocarcinoma: BAC vs. Stage I invasive adenocarcinoma. AJSP 28:1280-88, 2004.
Sheikh HA, Fuhrer K, Cieply K, Yousem S. p63 expression in assessment of bronchioloalveolar proliferations of the lung. Mod Pathol 17:1134-40, 2004.
Baksh FK, Finkelstein SD, Swalsky PA, Raja S, Sasatomi E, Luketich JD, Fernando HC, Yousem SA. Widespread molecular alterations present in stage I non-small cell lung carcinoma fail to predict tumor recurrence. Mod Pathol 16:28-34, 2003.
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