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CLINICAL EXPERTISE
Dr Triulzi is the medical director of the Centralized Transfusion Service in Pittsburgh supporting 15 area hospitals. The CTS is the largest transfusion service in the country issuing 125,000 red cells and 17,000 doses of platelets on an annual basis. The service supports large adult and pediatric organ and stem cell transplant programs and three level I trauma programs. Dr Triulzi also oversees a large Red Cell Reference laboratory analyzing more than 5,000 samples for antibody identification.
RESEARCH EXPERTISE
Dr Triulzi has long standing interests in the immunologic effects of transfusion and optimal use of blood components. He participated in multiple NIH funded clinical trials including the Viral Activation by Transfusion Study, Retrovirus Epidemiology in Donors II (REDSII) studies, and the Transfusion Medicine Hemostasis Clinical Trials Network (TMH CTN) studies. He serves as the site PI for both REDSIII and TMH networks. Current areas of investigation include: epidemiologic studies of transfusion and adverse outcomes such as TRALI and TACO and clinical and translational studies of the red cell storage lesion (RECESS).
Selected Publications:
View Dr. Triulzi's publications on PubMed.
Yazer MY, Triulzi DJ. Use of the rapid qualitative immunoassay for bacterial screening of whole blood platelets. Am J Clin Path 2010 133(4):564-8.
Yazer MY, Triulzi DJ, Hassett AC, Kiss JE. Cryoprecipitate from plasma frozen within 24 hours after phlebotomy contains acceptable levels of fibrinogen and VIIIC. Transfusion 2010;50:1014-8.
Qu L, Jenkins F, Triulzi DJ. Human Herpesvirus 8 (HHV-8) Genomes and Seroprevalence in US Blood Donors. Transfusion 2010;50:1050-6.
Kakaiya R, Triulzi DJ. Prevalence of HLA antibodies in remotely transfused or alloexposed volunteer blood donors. Transfusion 2010 50(6):1328-34.
Endres RO, Kleinman SH, Carrick DM, Steele WR, Wright DJ, Norris PJ, Triulzi D, Kakaiya, R, Busch MP. Identification of specificities of antibodies against human leukocyte antigens in blood donors. Transfusion 2010;50:1749-60.
Slichter SJ, Kaufman RM, Assman SF, McCullough J, Triulzi DJ, et al. Dose of prophylactic platelet transfusions and prevention of hemorrhage. New Eng J Med 2010;362:600-13.
Yazer MH, Triulzi DJ, Reciept of older RBCs does not predispose D-negative Recipients to anti-D alloimmunization. AJCP 2010;134:443-447.
Murphy EL, Fang J, Tu Y, Cable R, Hillyer CD, Sacher R, Triulzi D, Gotschall JL, Busch MP. Hepatitis C virus prevalence and clearance among US blood donors, 2006-2007: association with birth cohort, multiple pregnancies, and body mass index. J Infec Dis 2010;202:576-84.
Xiong Z, Cavaretta J, Qu L, Stolz DB, Triulzi D, Lee JS. Red cell microparticles show altered inflammatory chemokine binding and release ligand upon interaction with platelets. Transfusion 2011;51:610-21.
Sharma G, Parwani AV, Raval JS, Triulzi DJ, Benjamin RJ. Contemporary issues in transfusion medicine informatics. J Pathol Inform 2011:2;3.
Qu L, Triulzi DJ, Rowe DT, Jenkins FJ. Detection of HHV-8 (human herpesvirus-8) genomes in induced peripheral blood mononuclear cells (PBMCs) from US blood donors. Vox Sang. 2011 Apr;100(3):267-71.
Kleinman S, Triulzi DJ, Murphy EL, et al. The Leukocyte Antibody Prevalence Study-II (LAPS-II):a retrospective cohort study of transfusion related acute lung injury in recipients of high plasma volume human leukocyte antigen antibody positive or negative components. Transfusion 2011 Epub
DonadeeC, Raat NJH, Kanias T, Tejero J, Lee JS, Kelley E, Zhao X, Liu C, Reynolds H, Azarov I, Frizzell S, Meyer EM, Donnenberg AD, Qu L, Triulzi D, Kim-Shapiro DB, Gladwon MT. Nitric Oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion. Circulation 2011;124:465-76.
Gottschall JL, Triulzi DJ, Curtis B, Kakaiya RM, Busch MP, Norris PJ, Glynn SA, Carrick D, Wright DJ, Kleinman S. The frequency and specificity of human neutrophil antigen antibodies in a blood donor population. Transfusion 2011;51:820-7.
Rios JA, Schlumpf KS, Kakaiya RM, Triulzi DJ, et al. Blood donations from previously transfused or pregnant donors:a multicenter study to determine the frequency of alloexposure. Transfusion 2011;51:1197-1206.
Yazer MH, Raval JS, Triulzi DJ, Blumberg N. ABO-mismatched transfusions are not over-represented in febrile non-haemolytic transfusion reactions to platelets. Vox Sang 2012;102:93-184.
L Radkay, DJ Triulzi, MH Yazer. Low risk of hemolysis following transfusion of uncrossmatched RBCs. Immunohematology in press.
B McWilliams, MH Yazer, J Cramer, DJ Triulzi, and JH Waters. Incomplete pre-transfusion testing leads to surgical delays. Transfusion in press
Narick C, Triulzi DJ, Yazer MH. Transfusion Associated Circulatory Overload Following Plasma Transfusion. Transfusion 2012;52:160-165.
Triulzi DJ, Assmann SF, Strauss RG, et al. The impact of platelet transfusion characteristics on post-transfusion platelet increments and clinical bleeding in patients with hypoproliferative thrombocytopenia. Blood April 2012 online prepublication.
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