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CLINICAL EXPERTISE:
Diagnosis of immune-mediated diseases
RESEARCH EXPERTISE:
Tumor immunology, the tumor immunoenvironment, cancer immunotherapy, immune regulatory cells
PUBLICATIONS
View Dr. Shurin's publications on PubMed.
Tourkova I.L., Shurin G.V., Ferrone S., Shurin M.R. Interferon Regulatory Factor 8 Mediates Tumor-induced Inhibition of Antigen Processing and Presentation by Dendritic Cells. Cancer Immunol Immunother., 58:567-574, 2009.
Shurin G.V., Tourkova I.L., Kaneno R., Shurin M.R. Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism. J. Immunology, 183:137-144, 2009.
Shurin M.R., Potapovich A., Tyurina Y.Y., Tourkova I.L., Shurin G.V., Kagan V.E. Recognition of live phosphatidylserine-labeled tumor cells by dendritic cells: a novel approach to immunotherapy of skin cancer. Cancer Research 69(6): 2487-2496, 2009.
Kaneno R., Shurin G.V., Tourkova I.L., Shurin M.R. Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations. J. Translat. Medicine, 7:58, 2009.
Song E.Y., Shurin M.R., Tourkova I.L., Gutkin D.W., Shurin G.V. Epigenetic Mechanisms of Promigratory Chemokine CXCL14 Regulation in Human Prostate Cancer Cells. Cancer Research, 70(11):4394-4401. 2010.
Shurin M.R. MicroRNAs are invading the tumor microenvironment: Fibroblast microRNAs regulate tumor cell motility and invasiveness. Cell Cycle, 9(22): 4430-4431, 2010.
Kaneno R., Shurin G.V., Kaneno F.M., Naiditch H., Luo J., Shurin M.R. Chemotherapeutic agents in low noncytotoxic concentrations increase immunogenicity of human colon cancer cells. Cell. Oncol., 34(2):97-106, 2011.
Shurin M.R., Naiditch H., Zhong H., Shurin G.V. Regulatory dendritic cells: new targets for cancer immunotherapy. Cancer Biol. Ther., 11(11):988-992, 2011.
Naiditch H., Shurin M.R., Shurin G.V. Targeting myeloid regulatory cells in cancer by chemotherapeutic agents. Immunol. Res., 50(2-3):276-285, 2011.
Tkach A.V., Shurin G.V., Shurin M.R., Kisin E.R., Murray A.R., Young S-H., Star A., Fadeel B., Kagan V.E., Shvedova A.A. Direct effects of carbon nanotubes on dendritic cells induce immune suppression upon pulmonary exposure. ACS Nano, 5(7):5755-5762, 2011.
Sevko A., Kremer V., Falk C., Umansky L., Shurin M.R., Shurin G.V., Umansky V. Application of paclitaxel in low noncytotoxic doses supports vaccination with melanoma antigens in mice. J. Immunotoxicol., 2012, in press.
Michels T., Shurin G.V., Naiditch H., Sevko A., Umansky V., Shurin M.R. Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cells in vitro in a TLR4-independent manner. J. Immunotoxicol., 2012, in press.
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