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Research Interests:
Dr. Ranganathan's main area of interest is in the pathologic and clinical aspects of pediatric soft tissue and visceral tumors including hepatoblastomas, myofibroblastic lesions, Ewing's sarcoma and germ cell tumors. Currently, he is studying the histology and immunohistochemistry of hepatoblastomas and examining the relationship between pathologic features and patient prognosis. Dr. Ranganathan is also interested in pediatric heart transplant pathology, and the pathology and biology of post-transplant tumors especially post-transplant Hodgkin's-like lymphoproliferative disorder and spindle cell tumors.
Selected Publications:
Sarangarajan R, Dehner LP. Cranial and extracranial fasciitis of childhood: a clinicopathologic and immunohistochemical study. Hum Pathol. 1999; 30: 87-92.
Sarangarajan R, D Ashley Hill, Peter A. Humphrey, Michael G. Hitchcock, Louis P. Dehner, John D. Pfeifer. Primitive neuroectodermal tumors of the biliary and gastrointestinal tracts: clinicopathologic and molecular diagnostic study of two cases. Pediatr Dev Pathol 2001; 4: 185-191.
Ranganathan S, Jaffe R: Is there a difference between Hodgkin's disease and Hodgkin's-like post-transplant lymphoproliferative disorder, and why should that be of any interest? Editorial. Pediatr Transplantation 2004; 8: 6-8.
Ranganathan S, Webber S, Ahuja S, Jaffe R. Hodgkin's-like posttransplant lymphoproliferative disorder in children: Does it differ from posttransplant Hodgkin's lymphoma? Pediatr Dev Pathol. 2004; 7: 348-360.
Tan X, Apte U, Micsenyi A et al. Epidermal growth factor receptor: A novel target for Wnt/beta-catenin pathway in liver. Gastroenterology 2005; 129(1): 285-302.
Ranganathan S, Tan X, Monga SP. Beta-catenin and Met deregulation in childhood hepatoblastomas. Pediatr Dev Pathol. 2005; 8(4): 435-447.
Luo JH, Ren B, Keryanov S, Tseng GC, Rao UNM, Monga SP, Strom S, Demetris AJ, Nalesnik M, Yu YP, Ranganathan S, Michalopoulos GK. Transcriptomic and Genomic analysis of hepatocellular carcinomas and hepatoblastomas. Hepatology. 2006; 44: 1012-1024.
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