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Research Interests:
- Inhibition of c-Met and EGFR in Rodents and its effect on liver Regeneration.
- Investigation of the role of Decorin in Liver Biology.
- MicroRNA Expression Profiles in Regenerating Rat liver.
Selected Publications:
Lin Chih-Wen; Mars Wendy M.; Paranjpe S; et al. Hepatocyte Proliferation and Hepatomegaly Induced by Phenobarbital and 1,4-Bis [2-(3,5-Dichloropyridyloxy)] Benzene Is Suppressed in Hepatocyte-Targeted Glypican 3 Transgenic Mice. Hepatology, 2011, 54: 620-630.
Bhave VS, Paranjpe S, Bowen WC, Donthamsetty S, Bell AW, Khillan JS, Michalopoulos GK. Genes inducing iPS phenotype play a role in hepatocyte survival and proliferation in vitro and liver regeneration in vivo. Hepatology. 2011 Jul 7. doi: 10.1002/hep.24507. [Epub ahead of print].
Paranjpe S, Bowen WC, Tseng GC, Luo, J-H, Orr, A & Michalopoulos, GK. RNA Interference against hepatic Epidermal Growth Factor Receptor has Suppressive Effects on Liver Regeneration in Rats. Am J Pathol. 2010, 176:2669-2681.
Liu B, Bell, AW, Paranjpe, S, Bowen WC, Khillan JS, Luo J-H, Mars WM, Michalopoulos GK. Suppression of Liver Regeneration & Hepatocyte Proliferation in Glypican 3 Hepatocyte -Targeted Transgenic Mice. In Press, Hepatology 2010.
Liu B, Paranjpe S, Bowen WC, Bell AW, Luo JH, Yu YP, Mars WM, Michalopoulos GK. Investigation of the Role of Glypican 3 in Liver Regeneration and Hepatocyte Proliferation. Am J Pathol. 2009, 175:717-724.
Paranjpe, S, William C. Bowen, Aaron W. Bell, Kari Nejak-Bowen, Luo,J-H & George K. Michalopoulos. Cell Cycle Effects resulting from inhibition of HGF and its receptor c-met in regenerating rat liver by RNA interference. Hepatology. 2007 45 (6): 1471-1477.
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