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Department of Pathology
University of Pittsburgh
School of Medicine
S-417 BST
200 Lothrop Street
Pittsburgh, PA 15261
(412) 648-1260


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Department of Pathology - Faculty


Larry Nichols, M.D.


Dr. Nichols is a member of the Division of Anatomic Pathology. More information about this division is available here.

Dr. Nichols is the chief of the autopsy service of the University of Pittsburgh Medical Center-Presbyterian, which is a regional autopsy center for affiliated institutions (UPMC-Shadyside, UPMC-Mercy, UPMC-Passavant, UPMC-McKeesport and Magee) and private autopsies from non-affiliated institutions and individuals. He presents interesting and important autopsy cases to attending physicians and resident physicians at UPMC Presbyterian and other UPMC hospitals. He also teaches basic pathology and cardiac pathology in the University of Pittsburgh School of Medicine as well as teaching undergraduate pre-medicine students the study of disease in an evening course on his own time. He serves on the Patient Safety Committees of UPMC Presbyterian. He has signed out general surgical pathology biopsies and large specimens, as well as performing frozen sections at UPMC Presbyterian in the past. He has also staffed perinatal autopsies and signed out placentas and related specimens at the Magee-Womens Hospital in the past. He has worked as an all-around community hospital pathologist at UPMC-Southside in the past. Prior to coming to the University of Pittsburgh Medical Center, he did autopsies of AIDS patients from all of Los Angeles County at the Los Angeles County-University of Southern California Medical Center. He did his residency in pathology and his internship in internal medicine at the New England Deaconess Hospital-Harvard Medical School. Dr. Nichols holds an MD degree from the University of Wisconsin and an MA in philosophy (ethics and epistemology).

Office Location:
Rm. A610, Scaife Hall
Dept. of Pathology
UPMC-Presbyterian
200 Lothrop Street
Pittsburgh, PA 15213-2582

Contact Information:
Office Telephone: (412) 647-3936
Email Address: nicholsla@upmc.edu

Research Interests:

Dr. Nichols' research interests are in the use of autopsy findings for the improvement of patient safety (quality improvement), the causes of sudden unexpected death in hospital patients, the causes of death of transplant patients, the causes of death of lung cancer patients and aspects of cardiac pathology including microvascular coronary artery disease, coronary artery aneurysms, and cardiac sarcoidosis.

Selected Publications:

Nichols L, Lagana S, Parwani A. Coronary artery aneurysm: A review and hypothesis regarding etiology. Arch Pathol Lab Med 2008 May;132(5):823-8

Natalie AA, Nichols L, Bump GM. Platypnea-orthodeoxia, An uncommon presentation of patent foramen ovale. Am J Med Sci 2010 Jan;339(1):78-80

Lagana S, Parwani A, Nichols L. Cardiac sarcoidosis: A pathology-focused review. Arch Pathol Lab Med 2010 July;134(7):1039-1046.

Nichols L, Ocque RZ, Daly I. Zygomycosis associated with HIV infection and liver transplantation. Patholog Res Int 2011 Jan; 2011: Article ID 545981, 4 pages, doi:10.4061/2011/545981.

Buffington CW, Nichols L, Moran PL, Blix EUM. Direct connections between the spinal epidural space and the venous circulation in humans. Reg Anesth Pain Med 2011 Mar-Apr;36(2):134-139.

Monaco SE, Monaghan SA, Stamm JA, Khalbuss WE, Nichols L, Pantanowitz L. Toxoplasmosis in a Post-Transplant Bronchoalveolar Lavage: A Case Report. Diagn Cytopathol 2011 May 17. doi: 10.1002/dc.21646. [Epub ahead of print]

Smith MA, Roy S, Nestler R, Augustine B, Miller D, Parwani A, Nichols L. University of Pittsburgh Medical Center Remains Tracker: A novel application for tracking decedents and improving the autopsy workflow. J Pathol Inform. 2011;2:30. Epub 2011 Jun 14.



Copyright 1995-2012   
Department of Pathology   
Univ. Pittsburgh Sch. Medicine