Geoffrey Murdoch, MD, PhD
Associate Professor of Pathology
Dr. Murdoch is a member of the Division of Neuropathology.
UPMC Presbyterian Hospital
M8723 South Tower
200 Lothrop Street
Pittsburgh, PA 15213
Office Telephone: 412-647-6164
- BS - Yale University, 1976
- MD, PhD - University of California, San Diego, 1984
Clinical ExpertiseNeuropathology (adult and pediatric neoplastic, molecular neuro-oncology, fetal and developmental, dementing illnesses)
Research InterestsMy primary research interest is the contribution of innate immune mechanisms in developmental and neurodegenerative processes. One of the key approaches is to genotypic postmortem brain for functional polymorphisms in innate immune system genes and to analyze pathologic features as a function of genotype. The mechanistic bases for the revealed associations are then explored using cell culture model systems.
Selected PublicationsView Dr. Murdoch's publications on PubMed
Horbinski C, Kofler J, Kelly LM, Murdoch GH, Nikiforova MN. Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues. J Neuropathol Exp Neurol. 2009 Dec;68(12):1319-25.
Horbinski C, Kofler J, Yeaney G, Camelo-Piragua S, Venneti S, Louis DN, Perry A, Murdoch G, Nikiforova M. Isocitrate Dehydrogenase 1 Analysis Differentiates Gangliogliomas from Infiltrative Gliomas. Brain Pathol. 2011 Sept. 21(5):564-74. PMID: 21314850