|
Research Interests:
Dr. Monaghan's research interests are in acute leukemias and myeloid disorders, including myelodysplastic syndromes. She is interested in optimizing immunophenotypic analysis by flow cytometry to detect minimal residual disease and to detect abnormal patterns of antigen expression throughout cell maturation and, further, to investigate how this related to gene expression. She is also working on the effect of immunomodulatory therapies upon transcription factor expression in myeloid precursors and myeloma cells.
Selected Publications:
Pal R, Monaghan SA, Cortese Hassett A, Mapara MY, Schafer P, Roodman, GD, Ragni MV, Moscinski L, List A, Lentzsch S. Immunomodulatory derivatives (IMiDs) induce PU.1 downregulation, myeloid maturation arrest, and neutropenia. Blood, 2009, Jan 21; 115(3):605-14.
Willis MS, Monaghan SA, Miller ML, McKenna RW, Perkins WD, Levinson BS, Bhushan V, Kroft SH. Zinc-Induced Copper Deficiency. A report of Three Cases Initially Recognized on Bone Marrow Examination. Am J Clin Pathol. 2005 Jan; 123(1):125-31.
Monaghan SA, Peterson LC, James C, Marszalek L, Khoong A, Bacta DJ, Karpus WJ, Goolsby CL. Pan B-cell markers are not redundant in analysis of chronic lymphocytic leukemia. Cytometry. 2003 Nov; 56B(1):30-42.
|
