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Research Interests:
Dr. Kanbour-Shakir's interest is studying the pathogenesis, oncogenesis, host interaction, biology and immunogenetics of ovarian, endometrial and breast cancer and disease. Current research projects are on studies of growth factor, angiogenesis and kinases, and genetic instability in breast disease and cancer, ovarian epithelial tumors, endometriaI tumors and cytopathology.
Selected Publications:
Latimer JJ, Rubinstein WS, Johnson JM, Kanbour-Shakir A, Vogel VG, Grant SG. Haploinsufficiency for BRCA1 is associated with normal levels of DNA nucleotide excision repair in breast tissue and blood lymphocytes. BMC Med Genet. 2005 Jun 14;6(1):26
Keohavong P, Gao WM, Mady HH, Kanbour-Shakir A, Melhem MF. Analysis of p53 mutations in cells taken from paraffin-embedded tissue sections of ductal carcinoma in situ and atypical ductal hyperplasia of the breast. Cancer Lett. 2004 Aug 20;212(1):121-30.
Modugno F, Knoll C, Kanbour-Shakir A, Romkes M. A potential role for the estrogen-metabolizing cytochrome P450 enzymes in human breast carcinogenesis. Breast Cancer Res Treat. 2003 Dec;82(3):191-7.
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