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Research Interests:
Dr. Jaffe is interested in the histiocytic disorders of childhood, Langerhans' cell histiocytosis and related dendritic cell disorders, familial and acquired hemophagocytic lymphohistiocytosis, Rosai-Dorfman disease and juvenile xanthogranuloma. A consultation review service is offered. Dr. Jaffe in on the scientific committee of the Histiocyte Society and the steering committee of Nikolas Symposium for the Histiocytoses. . The pathology of pediatric transplantation, liver and small bowel and liver diseases of childhood are other interests.
Selected Publications:
Jaffe R. Disorders of Histiocytes, in: Hematopathology, Hsi ED, ed. Churchill Livingstone, Philadelphia,2007;513-550.
Weitzman S, Jaffe R. Uncommon histiocytic disorders; The non-Langerhans Cell Histiocytoses. Pediatr Blood & Cancer 2005;44:1-9.
Jaffe R. The Histopathology of Hemophagocytic Lymphohistiocytosis. In: Weitzman S, Egeler RM. Histiocytic Disorders of Children and Adults. Cambridge University Press, 2005:321-336.
Jaffe R. The Diagnostic Histopathology of Langerhans' Cell Histiocytosis. In: Weitzman S, Egeler RM. Histiocytic Disorders of Children and Adults. Cambridge University Press, 2005:14-39.
Vakkila J, Lotze MT, Riga C, Jaffe R. A basis for distinguishing cultured dendritic cells and macrophages in cytospins and fixed sections. Pediatr & Dev Pathol 2005;8:43-51.
Chikwava K, Jaffe R. Langerin (CD207) staining in normal pediatric tissues, reactive lymph nodes and childhood histiocytic disorders. Pediatr Dev Pathol 2004;7:607-614.
Jaffe R. Liver involvement in the histiocytic disorders of childhood. Pediatr Dev Pathol 2004;7:215-225.
Lotze MT, Jaffe R. Dendritic cells in disease: The identification of dendritic cells in cancer. In: Lotze MT, Thomson AW eds, Dendritic Cells, Biology and Clinical Applications,2nd ed. San Diego, Academic Press,2001:425-437.
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