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Research Interests:
Dr. Hamilton has research interests in the molecular markers of prognosis in pediatric brain tumors, and neurodegenerative diseases such as Alzheimer's, Lewy body dementia, ALS and Parkinson's disease. He is also Director of the Neuropathology Brain Bank and Case Editor for Brain Pathology, the journal of the International Society of Neuropathology. The Case of the Month is posted on the web (http://www.brainpathology.com) and three cases are published quarterly. The pediatric brain tumor research is conducted with Children's Hospital of Pittsburgh in collaboration with Dr. Ian Pollack, a pediatric neurosurgeon and the Children's Cancer Group (CCG) and Pedatric Brain Tumor Consortium As the diagnostic neuropathologist for the Neuropathology Core of the Alzheimer's Disease Research Consortium (ADRC) and head of the Neuropathology brain bank, Dr. Hamilton also collaborates with numerous dementia researchers.
Selected Publications:
McFadden K, Hamilton RL, Insalaco SJ, Lavine L, Al-Mateen M, Wang G, Wiley CA. Neuronal intranuclear inclusion disease without polyglutamine inclusions in a child. J Neuropathol Exp Neurol. 2005 Jun;64(6):545-52.
Lee JY, Finkelstein S, Hamilton RL, Rekha R, King JT Jr, Omalu B. Loss of heterozygosity analysis of benign, atypical, and anaplastic meningiomas.
Neurosurgery. 2004 Nov;55(5):1163-73.
Hamilton RL, Bowser R. Alzheimer disease pathology in amyotrophic lateral sclerosis. Acta Neuropathol (Berl). 2004 Jun;107(6):515-22.
Omalu BI, Wiley CA, Hamilton RL. February 2003: a 53-year-old male with new onset seizures. Brain Pathol. 2003 Jul;13(3):419-20, 423.
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