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Research Interests:
Dr. Giannoukakis' main research focus is to use genes and cells as drugs and medicines by which autoimmunity can be prevented or controlled. Broadly defined, autoimmunity refers to the phenomenon where a person's immune system begins to react against particular cells and tissues, leading to a disease state. One such example is type 1 diabetes mellitus where the body's immune cells seek out and eventually destroy the insulin-producing cells of the pancreas.
Selected Publications:
View Dr. Giannoukakis' publications on PubMed
Corcoran DL, Feingold E, Dominick J, Wright M, Harnaha J, Trucco M, Giannoukakis N, Benos PV. Footer: a quantitative comparative genomics method for efficient recognition of cis-regulatory elements. Genome Res. 2005 Jun;15(6):840-7.
Giannoukakis N. Pyridoxamine (BioStratum). Curr Opin Investig Drugs. 2005 Apr;6(4):410-8.
Trucco M, Giannoukakis N. Type 1 diabetes: MHC tailored for diabetes cell therapy. Gene Ther. 2005 Apr;12(7):553-4.
Machen J, Harnaha J, Lakomy R, Styche A, Trucco M, Giannoukakis N. Antisense oligonucleotides down-regulating costimulation confer diabetes-preventive properties to nonobese diabetic mouse dendritic cells. J Immunol. 2004 Oct 1;173(7):4331-41
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