Jon M. Davison, MD
Assistant Professor of Pathology


Dr. Davison is a member of the Division of Anatomic Pathology. He is also a member of the Gastrointestinal Pathology Center of Excellence.

Office Location:
UPMC Presbyterian, Suite A610.1
200 Lothrop Street
Pittsburgh, PA 15213
Contact Information:
Office Telephone: 412-647-6125
Fax: 412-647-6251
Email: davisonjm@upmc.edu

Education

  • BA - University of Notre Dame, 1990
  • MD - Pritzker School of Medicine, 2002
  • Residency - Anatomic Pathology, Johns Hopkins Department of Pathology, 2005
  • Fellowship - Gastrointestinal Pathology, Johns Hopkins Department of Pathology, 2006

Clinical Expertise

Gastrointestinal pathology, including pathology of the pancreas. I have a special interest in Barrett’s esophagus and esophageal neoplasia.

Research Interests

My primary research interest is the clinical, pathologic and molecular determinants of the behavior and outcomes of esophageal carcinoma and Barrett’s esophagus.

Specialties

Anatomic Pathology and Gastrointestinal Pathology

Selected Publications

View Dr. Davison's publications on PubMed

Radu OM, Foxwell T, Cieply K, Navina S, Dacic S, Nason KS, Davison JM. HER2 amplification in gastroesophageal adenocarcinoma: correlation of two antibodies using gastric cancer scoring criteria, H score, and digital image analysis with fluorescence in situ hybridization. American Journal of Clinical Pathology. 2012 Apr; 137 (4):583-94. PMID: 22431535.

Peery AF, Hoppo T, Garman KS, Dellon ES, Daugherty N, Bream S, Sanz AF, Davison J, Spacek M, Connors D, Faulx AL, Chak A, Luketich JD, Shaheen NJ, Jobe BA; Barrett's Esophagus Risk Consortium. Feasibility, safety, acceptability, and yield of office-based, screening transnasal esophagoscopy (with video). Gastrointestinal Endoscopy. 2012 May;75(5):945-953.e2. PMID: 22425272

Malhotra U, Zaidi AH, Kosovec JE, Kasi PM, Komatsu Y, Rotoloni CL, Davison JM, R C, Irvin, Hoppo T, Nason KS, Kelly LA, Gibson MK, Jobe BA. Prognostic value and targeted inhibition of survivin expression in esophageal adenocarcinoma and cancer-adjacent squamous epithelium. PLoS One. 2013; 8 (11):e78343. PMCID: PMC3817247. PMID: 24223792.

Saligram S, Chennat J, Hu H, Davison JM, Fasanella KE, McGrath K. Endotherapy for superficial adenocarcinoma of the esophagus: an American experience. Gastrointestinal Endoscopy. 2013 Mar 6. PMID: 23472998.

Ong CA,** Shapiro J,** Nason KS,** Davison JM,** Liu X, Ross-Innes C, O’Donovan M, Dinjens WN, Biermann K, Shannon N, Worster S, Schulz LK, Luketich JD, Wijnhoven BP, Hardwick RH, Fitzgerald RC. Three-gene immunohistochemical panel adds to clinical staging algorithms to predict prognosis for patients with esophageal adenocarcinoma. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology. 2013 Mar 18. PMID: 23509313.**Co-first author paper.

Gibson MK, Zaidi A, Davison JM, Sanz AF, Hough B, Komatsu Y, Kosovec JE, Bhatt A, Malhotra U, Foxwell T, Rotoloni CL, Hoppo T, Jobe BA. Prevention of Barrett esophagus and esophageal adenocarcinoma by smoothened inhibitor in a rat model of gastroesophageal reflux disease. Annals of Surgery. 2013 Jul; 258 (1):82-88. PMID: 23108119.

Singhi A, Goyal A, Davison JM, Regueiro MD, Roche RL, Sarangarajan Ranganathan. Pediatric autoimmune enteropathy: an entity frequently associated with immunodeficiency disorders. Modern Pathology. 2014 Apr;27(4):543-53. Epub 2013 Sep 20. PMID: 24051695

Davison JM, Ellis ST, Foxwell TJ, Luketich JD, Gibson MK, Kuan SF, Nason KS. MUC2 expression is an adverse prognostic factor in superficial gastroesophageal adenocarcinomas. Human Pathology. 2013 Oct 30. PMID: 24290360.

Batts KP, Ketover S, Krasinskas AM, Mitchell KA, Wilcox R, Westerhoff M, Rank J, Gibson J, Mattia AR, Davison JM, Naini BV, Dry SM, Yantiss RK. Appropriate use of special stains for identifying Helicobacter pylori: Recommendations from the Rodger C. Haggitt Gastrointestinal Pathology Society. American Journal of Surgical Pathology. 2013 Nov; 37 (11):e12-22. PMID: 24141174

Thakur PC, Davison JM, Stuckenholz C, Lu L, Bahary N. Dysregulated phosphatidylinositol signaling promotes endoplasmic-reticulum-stress-mediated intestinal mucosal injury and inflammation in zebrafish. Disease Models and Mechanisms. 2014;Jan 7(1):93-106. Epub 2013 Nov 21. PMID: 24135483

Davison JM, Yee M, Krill-Burger JM, Lyons-Weiler MA, Kelly LA, Sciulli CM, Nason KS, Luketich JD, Michalopoulos GK, LaFramboise WA. The degree of segmental aneuploidy measured by total copy number abnormalities predicts survival and recurrence in superficial gastroesophageal adenocarcinoma. PLoS One. 2014; 9 (1):e79079. PMCID: PMC3894223. PMID: 24454681.

Davison JM, Choudry H, Ramalingam L, Zhu B, Pingpank J, Nikiforova M, Bartlett DL, Pai RK. Clinicopathologic and molecular analysis of disseminated appendiceal mucinous neoplasms: identification of factors predicting survival and proposed criteria for a three-tiered assessment of tumor grade. Modern Pathology. Epub ahead of print 2014 Mar 14, PMID: 24633196

Davison JM, Hartman D, Singhi AD, Choudry HA, Pingpank JF, Ahrendt SA, Holtzman MP, Zureikat A, Zeh HJ, Ramalingam L, Nikiforova M, Bartlett DL, Pai RK. Loss of SMAD4 protein expression is associated with high tumor grade and poor prognosis in disseminated appendiceal mucinous neoplasms. American Journal of Surgical Pathology. 2014 May; 38(5):583-92. PMID: 24618609.

Landau MS, Hastings SM, Foxwell TJ, Luketich JD, Nason KS, Davison JM. Tumor budding is a pathologic predictor of lymph node metastasis in superficial esophageal adenocarcinoma. Modern Pathology. (in press).