Rm A515 Scaife
University of Pittsburgh
School of Medicine
Pittsburgh, PA 15261

Office Telephone: (412) 647-6203
Fax: (412) 647-5602
E-mail: Jordan@np.awing.upmc.edu

Characterization of expression and activity of cell cycle proteins in HIV encephalitis.

• 2000 Eleventh Annual Pathology Research Day Presentation Award
• 1998 Ninth Annual Pathology Research Day Presentation Award
• 1997 Eighth Annual Pathology Research Day Presentation Award
• 1991 Foerderer Fellowship, Thomas Jefferson University
• 1991 Alpha Epsilon Delta National Premedical Honor Society.

1. Jordan K.L., Haas, A.R., Logan, T.J., and Hall D.J. Detailed analysis of the basic domain of the E2F1 transcription factor indicates that it is unique among bHLH proteins. 1994. Oncogene. 9,1177-1185.
2. Logan T.J., Jordan K.L., and Hall D.J. Altered shape and cell cycle characteristics of fibroblasts expressing the E2F1 transcription factor. 1994. Mol. Biol. Cell. 5,667-678.
3. Logan T.J., Jordan K.L., and Hall D.J. Constitutive expression of wild-type and mutant E2F1 alters G0 and S phase transit following serum stimulation. 1996. Biochem. and Cell Biol. 74,21-28.
4. Jordan, K.L., Evans, D.L., Steelman, S. and Hall, D.J. Isolation of two novel cDNA's whose products associate with the amino-terminus of the E2F1 transcription factor. 1996. Biochemistry. 35(38): 12320-12328.
5. Logan, T.J., Jordan, K.L., Evans, D.E., and Hall, D.J. Altered cell shape is linked to increased p34cdc2 gene expression in fibroblasts expressing a mutant E2F-1 transcription factor. 1997. J. Cell. Biochem. 65:83-94.
6. Jordan-Sciutto, K.L., Logan, T.J., Norton, P., Derfoul, A., Dodge, G.R., and Hall, DJ. Reduction in fibronectin expression and alteration in cell morphology are coincident in NIH3T3 cells expressing a mutant E2F1 transcription factor. 1997. Exp. Cell Res.. 236(2):527-36.
7. Jordan-Sciutto, K.L. and Bowser, R. Alzheimer's disease and brain development: Common molecular pathways. 1998. Frontiers in Bioscience. 3:100-112. http://vega.crbm.cnrs-mop.fr/bioscience/1998/v3/d/jordan/3.htm
8. Jordan-Sciutto, K., Dragich, J., Walcott, D., and Bowser, R. The presence of FAC1 protein in Hirano bodies. 1998. Neuropathol. Appl. Neurobiol. 24:359-366.
9. Jordan-Sciutto, K.L. and Hall, D.J. A mutant E2F-1 transcription factor that affects the phenotype of NIH3T3 fibroblasts inefficiently associates with CyclinA/cdk2. 1998. Biochem and Cell Biol. 76(1):37-44.
10. Jordan-Sciutto, K.L., Dragich, J., and Bowser, R. DNA binding activity of the fetal Alz-50 clone1 (FAC1) protein is enhanced by phosphorylation. 1999. Biocem. Biophys. Res. Comm. 260:785-789.
11. Jordan-Sciutto, K.L., Dragich, J., Rhodes, J. L., and Bowser, R. Fetal Alz-50 clone 1, a novel zinc-finger protein, binds a specific DNA sequence and acts as a transcriptional regulator. 1999. J. Biol. Chem. 274(49):35262-35268.
12. Jordan-Sciutto, K.L., Morgan, K., and Bowser, R. Increased cyclin G1 immunoreactivity during Alzheimer's disease. 1999. J. Alzheimer's Disease. 1:409-417.
13. Jordan-Sciutto, K.L., Dragich, J., Caltagarone, J, and Bowser, R. Fetal Alz-50 clone 1 (FAC1) protein represses transcriptional activation by the myc associated zinc finger protein (ZF87/MAZ). 2000. Biochemistry. 39:3206-3215.
14. Jordan-Sciutto, K.L., Wang, G., Murphy-Corb, M., and Wiley, C. Induction of cell cycle regulators in simian immunodeficiency virus encephalitis. 2000 . American Journal of Pathology. In Press.
15. Jordan-Sciutto, K.L., Murray, B., Wiley, C.A., and Achim, C.L. Response of Cell Cycle Proteins to Neurotrophic Factor and Chemokine Stimulation in Human Neuroglia. Submitted.
16. Jordan-Sciutto, K.L., Caltagarone., J., Gittis, A, and Bowser, R. Fetal Alz-50 clone 1 interacts with the human homologue of KEAP1. Manuscript in Preparation