Research Interests:

Dr. Demetris' interests include the: 1) immunobiology of tolerance induction and chronic rejection; 2) the role of cytokines in growth control of biliary epithelium; and 3) digital pathology for enhancing transplantation pathology and research. Current translational and basic research projects include: a) study and development of experimental animal and human protocols to understand mechanisms of spontaneous operational tolerance to solid organ allografts; b) the role of IL-6 in biliary epithelial cell biology and chronic liver disease; and c) use of multiplexing and high resolution whole slide imaging in studying biological phenomena, including tolerance induction and biliary pathobiology.