Molecular Diagnostics Fellowship Program
- Mission Statement
- Molecular Genetic Pathology Training Environment
- Clinical and Research Training
- Fellow Responsibilities
- Method of Evaluation
Clinical and Research TrainingBoth clinical and investigative training is available in 1-3 year fellowship experiences. The primary purpose of the fellowship is to train the fellow to become an expert clinical consultant in molecular genetic testing as well as a qualified technical consultant in the choice of, development, evaluation and interpretation of clinical assays. This phase of training occupies the first year during which the fellow is expected to undertake several clinical projects designed to lead to presentable and/or publishable results. The fellow is also exposed heavily to day-to-day management issues associated with running a modern molecular genetic laboratory and should be qualified to direct such a laboratory upon completing the fellowship. The training offered will meet the training requirements of the joint American Board of Pathology - American Board of Medical Genetics Training Program in Molecular Genetic Pathology as well as (with an additional year of general genetics exposure) the Clinical Molecular Genetic Pathology Training program of the American Board of Medical Genetics. The Division is the training site for ABMG-CMG training in the Deptartment of Human Genetics' fellowship programs.
Fellows interested in further training in basic research have a variety of choices within or outside the Division of Molecular Genetic Pathology. Research in the Division includes active basic research programs dealing with mechanisms and mediators of programmed cell death, oxidative mechanisms of pulmonary, endocrine and neurologic disease, gene regulation in neoplasia, and viral pathogenesis and latency. There are also ongoing clinical and translational research efforts; these include clinico-pathologic correlations and improved assay method development in infectious, genetic and oncologic disorders, quantitative assessment of gene expression, the use of microfabricated chips in diagnostics, and regulatory, economic, ethical, and informatics issues associated with clinical Molecular Genetic Pathology. The Program also interfaces with a number of clinical user groups in the Medical Center, as well as investigators in the University of Pittsburgh's comprehensive Cancer Center as well as other faculty in the Department of Pathology to support developmental and clinical molecular genetic testing in a variety of cancers. There is a broad array of research opportunities elsewhere in the Department and the medical center to include particular strengths in cell growth, differentiation and regeneration, cancer, gene therapy, genomic sciences and quantitative genetics, neurosciences, immunology and molecular biology.