Coagulation Pathology Fellowship

Environmental Description

The Division is based in the Department of Pathology at the University of Pittsburgh and the Coagulation Laboratory is located at 3636 Blvd of the Allies, about 10 minutes from the main Oakland Campus. The laboratory has a client base of more than 50 hospitals in Western Pennsylvania, Eastern Ohio, and Northern West Virginia. It is a resource for physicians, hospitals, large medical centers, and national reference laboratories in the diagnosis and treatment of coagulation disorders. We provide technically advanced clinical and investigative capabilities, enabling us to provide specialty coagulation services that include medical consultation, testing, and education. The laboratory performs more than 7,000 tests a month to identify deficiencies of coagulation factors, natural anticoagulants, and to determine the presence of dysfunctional coagulation proteins, platelet, and acquired inhibitors.

The medical staff and laboratory personnel work closely with the Hemophilia Center of Western Pennsylvania and the Hemostasis and Thrombosis Clinic, also located in the same building. Housed under one roof, these entities provide care to hemophiliacs, von Willebrand patients, and individuals with other congenital and acquired coagulation bleeding and clotting disorders.

The Coagulation Laboratory is CAP and CLIA certified, and maintains licensures in Pennsylvania, Florida, Maryland, New York, Rhode Island, and West Virginia. We actively participate in the National Institutes of Health-sponsored research and FDA submission testing of reagent/test kits. The laboratory provides coagulation services to research investigators and conducts vendor-sponsored clinical evaluations of instrumentation and diagnostic kits, therapeutic field trials, and in-house test development.

The Centralized Transfusion Service (CTS) at The Institute For Transfusion Medicine (ITxM) is one of the largest and most innovative transfusion services in the country. CTS is a national leader in implementing the concept of centralized transfusion facilities and annually provides more than 110,000 red cells and 80,000 platelets to area hospitals representing more than 2/3 of all the transfusions in the Pittsburgh area. The core laboratory houses an AABB accredited red cell reference laboratory that tests more than 4,000 antibody samples each year from a three state region. ITxM also provides the blood center training environment for the fellows at Central Blood Bank, a community based blood center that collects and distributes blood and blood products to over 40 hospitals in the Western Pennsylvania, Northern West Virginia, and Eastern Ohio region. Annually, it draws blood from approximately 160,000 whole blood donors and 170,000 apheresis donors.

ITxM provides comprehensive laboratory testing in other areas related to transfusion medicine. It manages an active therapeutic apheresis service that includes the stem cell harvest program and a stem cell processing laboratory. ITxM has a medical staff consisting of 9 full-time physicians, and a Ph.D., all having faculty appointments at the University of Pittsburgh School of Medicine, Department of Medicine, Division of Hematology/Oncology; Department of Pathology; and Department of Medicine, Division of Hematology/Bone Marrow Transplant.