Richard J. Bodnar

709 Scaife
Department of Pathology
University of Pittsburgh
Pittsburgh, PA 15261
412-624-9366

rjb8@pitt.edu

Education

Institution Degree Conferred Field of study

University of Pittsburgh

BS 1993 Biochemistry & Biophysics, Minor Chemistry
University of Illinois   PhD 2002 Pharmacology

Publications:           

Xi X., Bodnar RJ., Li Z., Lam CT., Du X.; A critical role for the NITY sequence of the integrin b3 cytoplasmic domain in inside-out signaling and its regulation by calpain. (submitted to Journal of Cell Biology)

Bodnar RJ., Xi X., Li Z., Berndt M., Du X.; Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase -mediated phosphorylation at serine 166 of glycoprotein Ibb. JBC. Oct. 1, 2002, M208329200

Niu J., Scheschonka A., Druey K, Davis A., Kolenko V., Bodnar RJ., Voyno-Yasenetskaya T., Du X., Dunn MJ., Kehrl J., and Dulin NO.; RGS3 interacts with 14-3-3 via the N-terminal region distinct from RGS domain. Biochemical Journal May 1, 2002 BJ20020390

Englund GD., Bodnar RJ., Li Z., Ruggeri ZM., Du X.; Regulation of vWF binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal. (2001) JBC Vol. 276 (20) p. 16952-16959 

Dallasta LM., Wang G., Bodnar RJ., Draviam R.., Wiley CA., Achim CL., Hamilton RL.; Differential expression of intercellular adhesion molecule-1 in chronic murine retroviral encephalitis. (2000) Neuropath. App. Neurobio. Vol. 26, p. 332-341

Bodnar RJ., Gu M., Li Z., Englund GD., Du X.; The cytoplasmic domain of the platelet glycoprotein Iba is phosphorylated at serine 609. (1999) JBC Vol. 274 (47) p. 33474-33479

Abstracts:

Bodnar RJ., Xi X., Li Z., Berndt M., Du X.; Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase- mediated phosphorylation at serine 166 of glycoprotein Ibb. (2002) Blood, Vol. 100

Bodnar RJ., Xi X., Li Z., Berndt M., Du X.; Regulation of glycoprotein Ib-IX-von Willebrand factor Association through a PKA mediated inside-out signaling mechanism. (2002) Circulation

Bodnar RJ., Xi X., Li Z., Berndt M., Du X.; PKA mediated phosphorylation of glycoprotein Ibb at serine 166 negatively regulates glycoprotein Ib-IX-von Willebrand factor interaction. (2002) Pharmacologist

Englund GD., Bodnar RJ., Li Z., Ruggeri ZM., Du X.; Regulation of vWF binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal. (2000) Blood Vol. 96, (11), supplement 1, p. 620a

Bodnar RJ., Gu M., Li Z., Englund GD., Du X.; Phosphorylation at serine609 in the cytoplasmic domain of the platelet glycoprotein Iba modulates 14-3-3 binding. (1999) Blood, Vol. 94 ,(10), supplement 1, p. 371a 

Bodnar RJ., and Hamilton RL.; Effects of Zidovudine (AZT) and Saquinavir on retroviral infection of the central nervous system. (1996) Soc. Neurosci., Vol. 22, part 2, p. 939 

Sanders VJ., Bonaroti EA., Wang G., Bodnar RJ., Sarnacki P, and Achim CL.; Cytokine and neurotropic factor expression in HIV-infected human fetal brain microspheres transplanted in SCID mice striatum. (1996) Soc. Neurosci., Vol. 22, part 2, p939

Hamilton RL., Bodnar RJ., Wang G., and Wiley CA.; The effect of Zidovudine (AZT) on murine retroviral encephalitis. (1995) J. Neuropathol. Exp. Neurol., 54 (3), p. 348 

Hamilton RL., Bodnar RJ., Wang G., Klunk W., and Wiley CA.; Treatment of chronic retroviral encephalitis with Zidovudine (AZT) in a murine model. (1995) Soc. Neurosci., Vol. 21, part 1, p. 236

Hamilton RL., Bodnar RJ., Wang G., and Wiley CA.; The effect of AZT on retroviral encephalitis: a murine model. Presented at the sixth workshop on the pathogenesis of animal retroviruses, Philadelphia, PA Nov 17-19, 1994

Honors and Awards:

National Research Service Award #HL07829-06 (1998-2001)

American Society of Hematology Conference (2002) - Travel Award
Klaus R. Unna Award - 2002

1st place American Society for Pharmacology and Experimental Therapeutics student poster competition (2002)

4th place 12th Midwest Signal Transduction Symposium student poster competition (1999)