Division of Molecular Genomic Pathology- Diagnostic Services
Personalized Cancer Mutation Panel (PCMP) by Next Generation Sequencing
PCMP Test Details
PCMP List of Mutations
Brain Tumors
Glioma Panel (deletion of 1p, 19q, p16, PTEN, TP53)
MGMT promoter methylation
IDH1 and IDH2 mutations
Colorectal Cancer
Microsatellite Instability (MSI) analysisKRAS codons 12, 13, and 61 mutations
BRAF mutation
Lung Cancer
EGFR exons 18, 19, 20, and 21 mutationKRAS mutation
Thyroid Cancer
Thyroid Panel: BRAF, NRAS, HRAS, KRAS, RET/PTC, PAX8/PPAR γ; mutations (for freshly collected FNA samples and frozen tissue)Thyroid Panel: BRAF, NRAS, HRAS, and KRAS mutations by PCR and RET/PTC by FISH (for fixed FNA samples and FFPE tissue)
BRAF mutation
Thyroid LOH analysis, follicular cancer
Melanoma
BRAF and NRAS Mutations
Other Tests
Parathyroid Panel, LOH analysisPancreatic Panel, LOH analysis & KRAS mutation
Liver Panel, LOH analysis
Appendicial Panel, LOH analysis & KRAS mutation
Double primary testing for tumor de novo vs. metastasis
Tissue identity testing