Development Projects of the Clinical Chemistry Division


The research activities in the Division of Clinical Chemistry are centered around the programs of individual faculty members and represent investigations into both clinical and basic sciences. There are active collaborations in many projects with various departments in the School of Medicine, other schools at the University and also other institutions.

*Dr. Joseph Amenta has a long-standing interest in cellular protein turnover and its role in regulation of normal and neoplastic cell growth. Other areas of his research include: biochemical indicators in the assessment of fetal maturity and reproductive endocrinology.

*Dr. Gary Blank's work has focussed on the configuration and application of computer systems for management of laboratory information.

*The major research effort of Dr. Warren Diven has been in the understanding of the biochemical pathology of otitis media utilizing patient material and addressing specific issues through the use of an animal model. His work in the area of inherited diseases of metabolism has included: Gaucher's disease urea cycle enzyme deficiencies, and lysosomal storage diseases.

*Dr. K.N. Rao has worked in the area of environmental pathology and probed the etiogenesis of chemically induced cancers in animal models such that rationale for chemoprevention can be devised and established.

*The areas of research interest for Dr. Mohamed A. Virji involve the use of biochemical markers in the evaluation and management of cancer patients, biochemical indicators of rejection/organ failure in liver transplant, role of peptide hormones and growth factors in oncogenesis, and the pathogenesis of type II diabetes mellitus.

*Dr. Vijay Warty has worked on an in-vitro biochemical model to investigate the dynamics of vessel wall metabolism in the process of atherogenesis. Additionally, he has been involved in the studies on evaluation of novel immunosuppressive drugs in collaboration with Transplantation Surgery Division.

A number of these projects are supported through extramural funds.


wwwadmin@path.upmc.edu

Who's who -- wwwadmin