Medical Renal Biopsy / Electron Microscopy Faculty Sheldon Bastacky, MD Presbyterian: (412) 647-9612 Mission Statement The Medical Renal Biopsy / Electron Microscopy Center of Excellence is based at UPMC - Presbyterian Hospital, and is focused on providing diagnostic excellence in medical renal disease for patient care; providing education to medical students, pathology residents and nephrology fellows; and advancing knowledge through collaborative research projects. We work closely with nephrologists and other clinical physicians throughout the UPMC Health System and outside of the network of UPMC hospitals, providing comprehensive diagnostic interpretation of medical renal biopsies utilizing light microscopy with histochemical and immunohistochemical stains, immunofluorescence and electron microscopy. Our division participates in a variety of patient management and educational interdepartmental conferences with the divisions of Nephrology and Rheumatology. We also provide diagnostic interpretations of non-renal biopsies that require immunofluorescence or electron microscopy, including assessment of poorly differentiated tumors, metabolic storage disorders, and congenital anatomic disorders (e.g. immotile cilia syndrome). Our division evaluates approximately 400 native renal biopsies per year, and the Transplant Pathology Division assesses over 600 renal allograft biopsies. We have a glass slide and electron microscopy grid collection of a diverse group of medical renal diseases that are available to rotating residents. Residents have hands on exposure to state-of-the-art immunofluorescence and electron microscopy with digital imaging. Our research focuses on clinicopathologic correlations of native and allograft medical renal diseases and collaborations with basic scientists in the school of medicine using animal models to study a variety of renal diseases