Pathology Graduate Training Program
Cellular and Molecular Pathology (CMP) -
Current Graduate Students

Name: Ricardo Londono
Email: londono.ricardo@medstudent.pitt.edu
Lab Phone: 412-624-5252
Mentor Name: Stephen Badylak, MD, PhD

Education:
Name of school attended: Florida International University
Undergraduate degree: B.S. Electrical and Computer Engineering

Research Project Information:

Mechanisms of Biomaterial-Mediated Cardiac and Esophageal Repair

Publications:

ECM hydrogel coating mitigates the chronic inflammatory response to polypropylene mesh. Faulk DM, Londono R, Wolf MT, Ranallo CA, Carruthers CA, Wildemann JD, Dearth CL, Badylak SF. Biomaterials. 2014 Oct;35(30):8585-95. doi: 10.1016/j.biomaterials.2014.06.057. Epub 2014 Jul 16.

In vivo degradation of 14C-labeled porcine dermis biologic scaffold. Carey LE, Dearth CL, Johnson SA, Londono R, Medberry CJ, Daly KA, Badylak SF. Biomaterials. 2014 Sep;35(29):8297-304. doi: 10.1016/j.biomaterials.2014.06.015. Epub 2014 Jul 3.

Human NELL1 protein augments constructive tissue remodeling with biologic scaffolds. Turner NJ, Londono R, Dearth CL, Culiat CT, Badylak SF. Cells Tissues Organs. 2013;198(4):249-65. doi: 10.1159/000356491. Epub 2013 Dec 7.

Patch esophagoplasty: esophageal reconstruction using biologic scaffolds. Nieponice A, Ciotola FF, Nachman F, Jobe BA, Hoppo T, Londono R, Badylak S, Badaloni AE. Ann Thorac Surg. 2014 Jan;97(1):283-8. doi: 10.1016/j.athoracsur.2013.08.011. Epub 2013 Nov 20.

An assay to quantify chemotactic properties of degradation products from extracellular matrix. Sicari BM, Zhang L, Londono R, Badylak SF. Methods Mol Biol. 2014;1202:103-10. doi: 10.1007/7651_2013_37.

Polypropylene surgical mesh coated with extracellular matrix mitigates the host foreign body response. Wolf MT, Carruthers CA, Dearth CL, Crapo PM, Huber A, Burnsed OA, Londono R, Johnson SA, Daly KA, Stahl EC, Freund JM, Medberry CJ, Carey LE, Nieponice A, Amoroso NJ, Badylak SF. J Biomed Mater Res A. 2013 Jul 19. doi: 10.1002/jbm.a.34671. [Epub ahead of print]

Preparation and characterization of a biologic scaffold from esophageal mucosa. Keane TJ, Londono R, Carey RM, Carruthers CA, Reing JE, Dearth CL, D'Amore A, Medberry CJ, Badylak SF. Biomaterials. 2013 Sep;34(28):6729-37. doi: 10.1016/j.biomaterials.2013.05.052. Epub 2013 Jun 15.

Esophagus and regenerative medicine. Londono R, Jobe BA, Hoppo T, Badylak SF. World J Gastroenterol. 2012 Dec 21;18(47):6894-9. doi: 10.3748/wjg.v18.i47.6894.

Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials. Brown BN, Londono R, Tottey S, Zhang L, Kukla KA, Wolf MT, Daly KA, Reing JE, Badylak SF. Acta Biomater. 2012 Mar;8(3):978-87. doi: 10.1016/j.actbio.2011.11.031. Epub 2011 Dec 2. Erratum in: Acta Biomater. 2012 Jul;8(7):2871.

Consequences of ineffective decellularization of biologic scaffolds on the host response. Keane TJ, Londono R, Turner NJ, Badylak SF. Biomaterials. 2012 Feb;33(6):1771-81. doi: 10.1016/j.biomaterials.2011.10.054. Epub 2011 Dec 2.

Extracellular matrix degradation products and low-oxygen conditions enhance the regenerative potential of perivascular stem cells. Tottey S, Corselli M, Jeffries EM, Londono R, Peault B, Badylak SF. Tissue Eng Part A. 2011 Jan;17(1-2):37-44. doi: 10.1089/ten.TEA.2010.0188. Epub 2010 Sep 6.

Design and validation of a system to simulate coronary flexure dynamics on arterial segments perfused ex vivo. VanEpps JS, Londono R, Nieponice A, Vorp DA. Biomech Model Mechanobiol. 2009 Feb;8(1):57-66. doi: 10.1007/s10237-007-0117-7. Epub 2008 Feb 23.

Abstracts

Modeling the Immune Response to Allogeneic Pancreatic Islets. - Giorgio Raimondi, Jamie L. Haney, Ricardo Londono, Joyeeta Dutta-Moscato, James R. Faeder, and Yoram Vodovotz.

Effects of Biological Scaffold Decellularization on Macrophage Phenotype. - Londono, Ricardo; Turner, Neill; Keane, Tim; Badylak, Stephen F

Effects of Macrophage-Conditioned Media on Neural Stem Cell Migration and Proliferation. - Londono R; Crapo P; Badylak SF

Monocyte phenotype modulation with different levels of biologic scaffold decellularization. - Londono, R; Tottey, S; Badylak SF

Oxygen Dependant Mitogenic and Chemotactic Properties of Urinary Bladder Matrix and Small Intestine Submucosa on MG71 cells. - Londono R; Tottey S; Reign J; Badylak S.

Biological Assessment of a Novel Cyclic Bending Device for Ex-vivo Vascular Organ Culture - Londono, R; VanEpps, JS; Chew WD, and Vorp, DA.

Development of a Novel Device to Apply Coronary-Like Bending Motion to Intact Vascular Segments Perfused Ex-vivo. - Ricardo Londono; J. Scot VanEpps; Robert J. Toth; Alejandro Nieponice, M.D.; David A. Vorp, PhD.

Presentations

Society for Biomaterials, April 10-13, 2013 in Boston, Massachusetts, USA. "The Immune Response to Xenogeneic Acellular Biologic Scaffold Materials"