Microscopic Description -- Lymphadenopathy


MICROSCOPIC DESCRIPTION:

Peripheral Blood
WBC 15.2 10x9/L
RBC 4.45 10x12/L
Hgb 12.5 g/dL
Hct 36.6 %
MCV 82.3 fL
MCH 28.1 fL
MCHC 34.1 g/dL
RDW 11.9 %
PLT 254 10x9/L
Retic
Retic

Peripheral Blood Differential
Cell Type Percentage Abs. No.
Polys 11 % 1.67
Bands
Lymphs 38 % 5.78
Atyp. Lymphs 45 % 6.84
Monos 5 % 0.76
Eos 1 % 0.15
Baso
Blasts
Promyelos
Myelos
Metamyelos
NRBC/100 WBC

The peripheral blood smear was reviewed.

RED BLOOD CELL MORPHOLOGY:

Slight anisocytosis, slight poikilocytosis, polychromasia.

WHITE BLOOD CELL MORPHOLOGY:

Abundant atypical lymphocytes , some of which contain granules.

PLATELETS are adequate with occasional large forms seen.

BONE MARROW:

The marrow aspirate smear is adequate for interpretation with cellular spicules seen. Four aspirate smears and zero touch imprints reviewed.

Bone Marrow Differential
Blasts 2.3 %
Promyelos 1.5 %
Myelos 10.2 %
Metamyelos 6.4 %
Bands 9 %
PMN 10.2 %
Eos Myelo/Metas 0.8 %
Eos Bands
Eos Segs 1.5 %
Basos 0.4 %
Monos 5.3 %
Pronormos 3.8 %
Normos 24.4 %
Lymphos 24.1 %
Plasma Cells 0.4 %
Others
Myeloid:Erythroid Ratio 1.7
Total # of cells counted: 300

Atypical lymphocytes were seen upon scanning. Histiocytes with cytoplasmic debris as well as many naked nuclei are noted.

The MYELOID/ERYTHROID RATIO is unremarkable.

ERYTHROID MATURATION is complete and slightly megaloblastoid.

MYELOID MATURATION is complete and slightly megaloblastoid with asychrony of maturation and retention of primary granules.

MEGAKARYOCYTES are present. Megakaryocytes include occasional hypersegmented forms.

Flow Cytometry


Case 

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