MICROSCOPIC DESCRIPTION:
Sections of the liver demonstrate multiple coalescing abscesses, epithelioid granulomas, caseation necrosis, Langhan's type giant cells and chronic inflammation.
The portal vein is thrombosed, with granulomas and abscesses present in it's wall. The surrounding liver shows early bridging fibrosis of portal tracts, steatosis, focal hepatocyte necrosis and cholestasis.
Sections of the lung demonstrate epithelioid granulomas with caseation necrosis, chronic inflammation and Langhan's giant cells.
Sections of the kidney, ileum and colon also demonstrate focal microscopic granulomas with necrosis, inflammation and occasional giant cells.
