Final Diagnosis -- Follicular Hyperplasia with Focal Monocytoid B-Cell Proliferation


Final diagnosis comment:

Warthin-Starry stain is positive for rod-like bacilli, strongly suggestive of cat scratch disease. Clinical correlation is required.

What is the criteria for a diagnosis of cat-scratch disease?

The clinical diagnosis of cat scratch disease can be made when three of the four following critteria are met (all four in an atypical case):

Clinical features of cat scratch disease:

Morphologic findings associated with cat scratch disease in the lymph node:

Bartonella henselae:

Identification of Bartonella henselae

By Culture:

By serology:

By polymerase chain reaction (PCR) detection of B. henselae DNA:


Contributed by Mark Fung, MD

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