Contributed by Swaminathan Rajendiran,MD and Sheldon Bastacky, MD
Published on line in November 1998
PATIENT HISTORY:
The patient is a 61-year-old man with advanced, systemic non-Hodgkin's lymphoma, presenting with renal failure and microscopic hematuria of several weeks duration. Pertinent history is remarkable for chronic NSAID use. Review of systems is remarkable for edema.
Kidneys are bilaterally enlarged sonographically. The clinical differential is lymphomatous infiltration of kidneys versus interstitial nephritis secondary to NSAID use.
LABORATORY DATA:
Sr.Creatinine | 10.3mg% |
BUN | 113mg% |
Creatinine Clearance | 4 |
Urine Sediment | Hyaline, rare fine granular cast 5-10 RBCs/ HPF 10-20 WBCs/HPF |
Urine Culture | Negative |
Urine Protein | 114 mg/24 hrs |