MICROSCOPIC DESCRIPTION:
The tumor is composed mostly of mesenchymal-appearing neoplastic cells, predominately chondrocytes, separated by extracellular chondroid matrix. These cells are arranged in irregular lobules, surrounded by fibrous bands. Islands of atypical epithelial cells, some of them with gland formation, are present adjacent to chondroid areas. Cytologic atypia, including cellular and nuclear pleomorphism, double nucleation and mitotic figures is present in the chondrocytes. Irregular pleomorphic nuclear features with chromatin clumping and prominent nucleoli characterize the epithelial component of the tumor. Acellular necrotic areas are present. No normal salivary gland tissue is identified.