Michelle A. Wood-Trageser, PhD
Dr. Wood-Trageser is a research instructor with the Division of Transplant Pathology.
200 Lothrop Street
Pittsburgh, PA 15213
Lab Telephone: 412-624-1304
- BS - Elizabethtown College, 2004
- PhD - University of Pittsburgh, 2009
As a mentee of Dr. A. J. Demetris, Dr. Wood-Trageser's research will focus on the genetic analysis of causative mutations in cholangiocarcinoma and how these mutations correlate to the immunologic phenotype of these tumors. In addition, our studies will focus on immunologic tolerance through mechanisms of MHC class II downregulation. Dr. Wood-Trageser works with the Research Histology Services core laboratory to assist in management of large projects and clinical trials. She also assists in development of multiplex immunostaining assays for mechanistic studies.
Dr. Wood-Trageser's research expertise is in:
- Molecular Biology
- Cell Biology
- Mouse Models
Awards and Honors
- Dorothy Lyet Research Endowment, Summer Research Stipend, Elizabethtown College, 2002, 2003
- Beta Beta Beta, Biological Honors Society, Elizabethtown College, 2003 - 2004
- Distinguished Student Award, Elizabethtown College, 2003, 2004
- Stephen L. Phillips Scientific Achievement Award, University of Pittsburgh, School of Medicine, 2008
- Gary Betty Scholar, University of Michigan, 2009
- Trainee Day Travel Award, Endocrine Society, 2009
- Outstanding Abstract Award, Endocrine Society, 2011
- Lalor Foundation Travel Fellow, Society for the Study of Reproduction, 2014
- Cornelia Post Channing New Investigator Award, Society for the Study of Reproduction, 2014
- Dr. Paul M. Rike Fellowship Award, Magee-Womens Research Institute, University of Pittsburgh, 2014
Selected PublicationsView Dr. Wood-Trageser's publications on PubMed
- Heaton, J.H.*, M. A. Wood*, A.C. Kim, L.O. Lima, F.M. Barlaskar, M.Q. Almeida, M.C.B.V. Fragoso, R. Kuick, A.M. Lerario, D.P. Simon, I.C. Soares, E. Starnes, D.G. Thomas, A.C. Latronico, T. J. Giordano, G.D. Hammer. Progression to Adrenocortical Tumorigenesis in Mice and Humans through Insulin-like Growth Factor 2 and β-catenin. American Journal of Pathology. 181(3):1017-33, 2012. PMCID: PMC3432433.
*Both authors contributed equally to this work.
- Wood, M.A., A. Acharya, I. Finco, M.J. Elston, M.D. Tallquist, G.D. Hammer. Fetal Adrenal Capsular Cells Serve as a Progenitor Cell Niche for Steroidogenic and Stromal Adrenocortical Cell Lineages in Mice. Development. 140:4522-4532, 2013. PMCID: PMC3817941.
- Wood-Trageser, M.A., F. Gurbuz, S.A. Yatsenko, E.P. Jeffries, L. D. Kotan, U. Surti, D.M. Ketterer, J. Matic, J. Chipkin, H. Jiang, M.A. Trakselis, A.K. Topaloglu, and A. Rajkovic. MCM9 mutations are associated with ovarian failure, short stature and chromosomal instability. American Journal of Human Genetics. 95(6):754-62, 2014. PMCID: PMC4259971.
- Al Asiri, S.*, S. Basit*, M.A. Wood-Trageser*, S.A. Yatsenko, E.P. Jeffries, U. Surti, D.M. Ketterer, S. Afzal, K. Ramzan, M. Faiyaz-Ul Haque, H. Jiang, M.A. Trakselis, and A. Rajkovic. Exome sequencing identifies MCM8 mutation in ovarian failure and chromosomal instability. Journal of Clinical Investigation. 125(1):258-262, 2015. PMCID: PMC4382257.
*Authors contributed equally to this work.
- Katari S., M.A. Wood-Trageser, H. Jiang, E. Kalynchuk, R Muzumdar, S.A. Yatsenko, and A. Rajkovic. Novel Inactivating Mutation of the FSH Receptor in Two Siblings of Indian Origin with Premature Ovarian Failure. Journal of Clinical Endocrinology and Metabolism. 100(6):2154-2157, 2015. doi: 10.1210/jc.2015-1401.
- Yatsenko, S.A., H.A. Bakos, K. Vitullo, M. Kedov, A. Kishore, B.J. Jennings, U. Surti, M.A. Wood-Trageser, S. Cercone, A.N. Yatsenko, A. Rajkovic, and A. Iannaccone. High-resolution microarray analysis unravels complex Xq28 aberrations in patients and carriers affected by X-linked blue cone monochromacy. Clinical Genetics, 89(1): 82-87, 2016. PMCID: PMC4758204.