Steven H. Swerdlow, MD
Professor of Pathology



Dr. Swerdlow is the director of the Division of Hematopathology. He oversees and participates in the varied clinical, educational and research activities of the 9 faculty member division.

Office Location:
Suite G300
UPMC Presbyterian
Pittsburgh, PA 15213
Contact Information:
Office Telephone: 412-647-5191
Fax: 412-647-4008
Email: swerdlowsh@upmc.edu

Education

  • MD - Harvard Medical School, 1975

Certifications

National Board of Medical Examiners, 1976

American Board of Pathology:

  • Anatomic & Clinical Pathology 1979
  • Recertification (2005-2014), 2005
  • Recertification (2013-2023), 2013
  • Maintenance of Certification Program, 2013-Present

Specialties

Hematopathology

Awards and Honors

  • Listed in America's Top Doctors (US News & World Report top 1% in specialty) 2001-2013
  • Outstanding Teaching in Clinical Pathology Resident Award, 1994, 2001, 2009
  • Trustee, American Board of Pathology
  • Elected Member, International Lymphoma Study Group

Clinical Expertise

Dr. Swerdlow's expertise is in hematopathology with an emphasis on lymph node and related tissue diagnostic hematopathology using a multiparameter approach that incorporates morphology, flow cytometric and immunohistochemical phenotype, cytogenetic, molecular, and clinical data. He is also responsible for oversight of the Division's varied clinical activities that include general hematology laboratories, a flow cytometry laboratory, and a variety of diagnostic services.

Research Interests

Dr. Swerdlow's research efforts involve the use of a multiparameter approach to better define, diagnose and understand selected B-cell and some T/NK lymphomas and the post-transplant lymphoproliferative disorders. Areas of investigation include the following (some in collaboration with other investigators either at the University of Pittsburgh or elsewhere): The relationship of CLL/SLL to the B-cell follicle, lymphoplasmacytic infiltrates in the breast, IgG4 expression in Zoon’s balanitis, SNP analyses of PTLD, in situ follicular lymphomas, T follicular helper cell antigen expression in T and B cell proliferations, S100 + T-cell neoplasms, ALK negative anaplastic large cell lymphomas and high throughput cytogenetic testing.

Selected Publications

View Dr. Swerdlow's publications on PubMed

Peer-Reviewed Articles

Craig, F.E., Ohori, N.P., Gorrill, T., and Swerdlow, S.H. Flow Cytometric Immunophenotyping of Cerebrospinal Fluid Specimens, American Journal of Clinical Pathology, 135:22-34, 2011.

Visco, C., Malik, J.T., Hoeller, S., Xu-Monette, Z.Y., Wiggins, M.L., Liu, J., Sanger, W.G., Chang, J., Ranheim, E.A., Swerdlow, S.H., Gradowski, J.D., Serrano, S., Gascoyne, R.D., Chan, W.C., Liu, Z., Campo, E., Wang, H-Y., Liu Q., Dave, S., Olsen, B., Tzankov, A., Young, K.H. Molecular Characteristics of Mantle Cell Lymphoma Presenting with Clonal Plasma Cell Component. Am J Surg Pathol, 35(2)177-189, 2011.

Gibson, S.E., Swerdlow, S.H., Felgar, R.E. Natural killer (NK) cell subsets and NK-like T-cell populations in benign and neoplastic B-cell proliferations vary based on clinicopathologic features, Human Pathology, 2011:42:679-87.

Gibson, S.E., Swerdlow, S.H., Ferry, J.A., Surti, U., Dal Cin, P., Harris, N.L., Hasserjian, R.P. Reassessment of small lymphocytic lymphoma in the era of monoclonal B-cell lymphocytosis (MBL), Haematologica 2011;96(8):1144-1152.

Edinger, J.T., Lorenzo, C.R., Breneman, D.L., Swerdlow, S.H. Primary cutaneous marginal zone lymphoma with subclinical cutaneous involvement and biclonality, J Cut Pathol, 2011:38:724-730.

Gibson, S.E., Swerdlow, S.H., Craig, F.E., Surti, U., Cook, J.R., Nalesnik, M.A., Lowe, C., Wood, K.M., Ranganathan, S., and Bacon, C.M. EBV-positive extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the post-transplant setting: a distinct type of post-transplant lymphoproliferative disorder? Am J Surg Pathol, 2011:35(6):807-815.

Pongpruttipan, T., Sukpanichnant, S., Assanasen, T., Wannakrairot, P., Boonsakan, P., Kanoksil, W., Kayasut, K., Mitarnun, W., Khuhapinant, A., Bunworasate, U., Puavilai, T., Bedavanija, A., Garcia-Herrera, A., Campo, E., Cook, J., Choi, J., Swerdlow, S.H. Extranodal NK/T-cell lymphomas, nasal type, includes cases of natural killer cell, αβ, γδ, and αβ/γδ T-cell Origin: a comprehensive clinicopathologic and phenotypic study. Am J Surg Pathol 3 February, 2012. doi: 10.1097/PAS.0b013e31824433d8. PMID: 22314189.

Gradowski, J.F., Sargent, R.L., Craig, F.E., Cieply, K., Fuhrer, K., Sherer, C., Swerdlow, S.H. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma with Cyclin D1 Positive Proliferation Centers Do Not Have CCND1 Translocations or Gains and Lack SOX11 Expression. Am J Clin Pathology, 2012, 138:132-139. [Selected for CME activity.]

Aggarwal, N., Swerdlow, S.H., Kelly, L.M., Ogilvie, J.B., Sathanoori, M., Nikiforova, M.N., Nikiforov, Y.E. Thyroid carcinoma-associated genetic mutations also occur in thyroid lymphomas. Modern Pathology, 2012, 25, 1203-1211.

Royo C, Navarro A, Clot G, Salaverria I, Giné E, Jares P, Colomer D, Wiestner A, Wilson WH, Vegliante MC, Fernandez V, Hartmann EM, Trim N, Erber WN, Swerdlow SH, Klapper W, Dyer MJ, Vargas-Pabón M, Ott G, Rosenwald A, Siebert R, López-Guillermo A, Campo E, Beà S. Non-nodal type of mantle cell lymphoma is a specific biological and clinical subgroup of the disease (letter to editor). Leukemia, 2012 26(8):1895-1898.

Moroch J., Copie-Bergman C., de Leval L., Plonquet A., Martin-Garcia N., Dalfau-Larue M.H., Molinier-Frenkel V., Belhadj K., Haioun C., Audouin J., Swerdlow S.H., Marafioti T., Gaulard P. Follicular Peripheral T-cell Lymphoma Expands the Spectrum of Classical Hodgkin Lymphoma Mimics. Am J Surg Pathol., 2012 Nov; 36(11):1636-1646.

Pongpruttipan T, Cook JR, Reyes-Mugica M, Sphar JE, Swerdlow SH. Pulmonary MALT lymphoma associated with granulomatous inflammation in a child with chromosome 22q11.2 deletion syndrome (DiGeorge syndrome), J Pediatr, 2012 Nov;161(5):954-958.

Hoeller S., Zhou Y., Kanagal-Shamanna R., Xu-Monette Z.Y., Hoehn D., Bihl M., Swerdlow S.H., Rosenwald A., Ott G., Said J., Dunphy C.H., Buese-Ramos C.E., Lin P., Wang M., Miranda R.N., Tzankov A., Medeiros L.J., Young K.H. Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic and molecular study. Human Pathology, 2013, Jan; 44(1):110-21.

Pillai RK, Sathanoori M, Van Oss SB, Swerdlow SH. Double-hit B-cell Lymphomas with BCL6 and MYC Translocations are Aggressive Frequently Extranodal Lymphomas Distinct from BCL2 Double-hit B-cell Lymphomas. Am J Surg Pathol, (in press).

Rollins-Raval, M.A., Marafioti, T., Swerdlow, S.H., Roth, C.G. The number and growth pattern of plasmacytoid dendritic cells vary in different types of reactive lymph nodes: an immunohistochemical study. Human Pathology, (in press).

Wilson, A., Swerdlow, S.H., Przbylski, G.K., Surti, U., Choi, J., Campo, E., Trucco, M.M., Van Oss, B., Felgar, R.E. Intestinal γδ T-cell lymphomas are most frequently of type II Enteropathy-Associated T-cell type. Human Pathology, (in press).

Reviews, Invited Published Papers, Conference and Symposia Proceedings, Monographs, Books and Book Chapters

Swerdlow, S.H., Pathology. In Dharnidharka, V.R., Green, M., Webber, S.A., (Eds.): Transplant Lymphoproliferative Disorders, Springer, 89-104, 2010

Swerdlow, S.H., Craig, F.E.: Iatrogenic immunodeficiency associated lymphoproliferative disorders. In: Jaffe, E.S., Harris, N.L., Vardiman, J.W., Campo, E., Arber, D.A. eds. Hematopathology, Harcourt Health Sciences, 2011, 854-866

Cousar, J.B., Macon, W.R., McCurley, T.L., Swerdlow, S.H. Lymph Nodes. In Mills, S.E., Carter, D., Greenson, J., Reuter, V., Stoler, M., (Eds.): Lymph Nodes, Sternberg's Diagnostic Surgical Pathology, 5th Edition, Wolter Kluwer/Lippincott Williams & Wilkins, 2010, pp. 681-744.

Campo, E., Swerdlow, S.H., Pileri, S., Stein, H., Harris, N.L., Jaffe, E.S. The 2008 WHO Classification of Lymphoid Neoplasms - Evolving Concepts and Practical Applications. BLOOD, 2011:117(19)5019-5032.

Lin, P., Molina, T.J., Cook, J. R., Swerdlow, S.H. Lymphoplasmacytic Lymphoma and Other Non-Marginal Zone Lymphomas With Plasmacytic Differentiation: A report of the 2009 Society for Hematopathology/European Association for Haematopathology Workshop, Am J Clin Pathol 2011;136:195-210.

Molina, T.J., Pei, L., Swerdlow, S.H., Cook, J.R. Marginal Zone Lymphomas With Plasmacytic Differentiation and Related Disorders: A report of the 2009 Society for Hematopathology/European Association for Haematopathology Workshop , Am J Clin Pathol 2011;136:211-225.

Garcia C., Swerdlow S.H. Hematopoietic Tumors of the Breast. In: Dabbs, D. (Ed.) Breast Pathology. Philadelphia: Elsevier; 2012:740-766.

Papathomas, T.G., Venizelos, I., Dunphy, C.H., Said, J.W., Wang, M.L., Campo, E., Swerdlow, S.H., Chan, J.C., Bueso-Ramos, C., Weisenburger, D.D., Medeiros, L. J., Young, K.H. Mantle Cell Lymphoma as a Component of Composite Lymphoma: Clinicopathological Parameters and Biological Implications, “Progress in Pathology”, Human Pathology, 2012, 43:467-480.

Swerdlow SH. Lymphoma Classification and the Tools of Our Trade: an introduction to the 2012 USCAP Long Course. Mod Pathol, 2013 Jan;26 Suppl 1:S1-S14. doi: 10.1038/modpathol.2012.177. PMID: 23281432.

Swerdlow, S.H., Quintanilla-Martinez, L., Willemze, R., Kinney, M.C. Cutaneous B-cell lymphoproliferative disorders: Report of the 2011 Society for Hematopathology/European Association for Haematopathology workshop, Am J Clin Pathology, 2013, 139:515-535. [Selected for CME activity.]

Song, S.X., Willemze, R., Swerdlow, S.H., Kinney, M.C. Said, J.W. Mycosis fungoides: Report of the 2011 Society for Hematopathology/European Association for Haematopathology Workshop, Am J Clin Pathology, 2013, 139:466-490.

Sarantopoulos, G.P., Palla, B., Said, J.W., Kinney, M.C., Swerdlow, S.H., Willemze, R., Binder, S.W. Mimics of Cutaneous Lymphoma: Report of the 2011 Society for Hematopathology/European Association for Haematopathology Workshop, Am J Clin Pathology, 2013, 139:536-551.

Quintanilla-Martinez, L., Jansen, P.M., Kinney, M.C., Swerdlow, S.H., Willemze, R. Non-mycosis fungoides cutaneous T-cell lymphomas: Report of the 2011 Society for Hematopathology/European Association for Haematopathology workshop, Am J Clin Pathology, 2013, 139:491-514.