Aatur D. Singhi, MD, PhD

Dr. Singhi is a member of the Division of Anatomic Pathology.
Office Location:
Scaife Hall, Room 616.2
200 Lothrop Street
Pittsburgh, PA 15213
Contact Information:
Office Telephone: 412-864-1508
Email: singhiad@upmc.edu


  • MD- Case Western Reserve University, 2007
  • PhD - University of Illinois at Chicago, 2005

Clinical Expertise

Dr. Singhi is a surgical pathologist with subspecialty training in gastrointestinal, liver and pancreatobiliary pathology. His diagnostic expertise includes both neoplastic and non-neoplastic diseases of the gastrointestinal system, liver, biliary tract and pancreas.

Research Interests

Dr. Singhi's research efforts are primarily translational and revolve around clinicopathologic studies and molecular characterization of gastrointestinal tract, liver and pancreatobiliary diseases to improve diagnosis, accurate prognostication, and the development of new treatment strategies.


Gastrointestinal and Pancreatobiliary Pathology


Board Certified in Anatomic Pathology and Clinical Pathology

Awards and Honors

  • 2012 - AACR-FNAB Fellows Grant for Translational Pancreatic Cancer Research
  • 2012 - Roger Haggit Gastrointestinal Pathology Society USCAP Abstract Award
  • 2010-2011 - Chief Resident, Department of Pathology, Johns Hopkins Hospital
  • 2005 - Finalist, F. Merlin Bumpus Junior Investigator Award, Lerner Research Institute, Cleveland Clinic
  • 2003-2005 - Susan G. Komen Breast Cancer Foundation Dissertation Research Award

Selected Publications

View Dr. Singhi's publications on PubMed

Singhi, A.D., Jain, D., Kakar, S., Wu, T.T., Yeh, M.M., and Torbenson, M. Reticulin Loss in Benign Fatty Liver: An Important Diagnostic Pitfall When Considering a Diagnosis of Hepatocellular Carcinoma. Am. J. Surg. Pathol. 2012 May; 36(5): 710-5.

Singhi, A.D., Cimino-Mathews, A., Jenkins, R.B., Lan, F., Fink, S., Nassar, H., Vang, R., Fetting, J., Sukumar, S., De Marzo, A., and Argani, P. MYC Gene Amplification is Often Acquired in Lethal Distant Breast Cancer Metastases of Unamplified Primary Tumors. Mod. Pathol. 2012 Mar; 25(3): 378-87.

Singhi, A.D., Califano, J, and Westra, W.H. High risk human papillomavirus is not a common etiologic agent in nasopharyngeal carcinoma. Head Neck. 2012 Feb; 34(2): 213-8.

Singhi, A.D. and Montgomery, E.A. Liposarcomas. Surg. Pathol. Clinics. 2011 Sept; 4(3): 963-994.

Salih, K.H., Singhi, A.D., and Montgomery, E.A., Selected Lesions Featuring Giant Cells. Surg. Pathol. Clinics. 2011 Sept; 4(3): 887-913.

Singhi, A.D., Hruban, R.H., Fabre, M., Imura, J., Schulick, R., Wolfgang, C., and Ali, S.Z. Peripancreatic Paragangliomas: A Potential Diagnostic Challenge in Cytopathology and Surgical Pathology. Am. J. Surg. Pathol. 2011 Oct; 35(10): 1498-504.

Singhi, A.D., Adsay, N.V., Swierczysnki, S.L., Torbenson, M., Anders, R.A., Hruban, R.H., and Argani, P. Hyperplastic Luschka Ducts: A Mimic of Adenocarcinoma in the Gallbladder Fossa. Am. J. Surg. Pathol. 2011 Jun; 35(6): 883-90.

Singhi, A.D., Mahklouf, H., Mehrotra, A., Goodman, Z., Anders, R.A., Drebber, U., Dienes, H., and Torbenson, M. Segmental atrophy of the liver: a distinctive pseudotumor of the liver with variable histologic appearances. Am. J. Surg. Pathol. 2011 Mar; 35(3): 364-71.

Singhi, A.D. and Montgomery, E.A. Gastrointestinal Tract Langerhans Cell Histiocytosis: A Clinicopathologic Study of 12 Patients. Am. J. Surg. Pathol. 2011 Feb; 35(2): 305-10.

Singhi, A.D. and Montgomery, E.A. Colorectal granular cell tumor: a study of 24 cases Am. J. Surg. Pathol. 2010 Aug; 34(8): 1186-92.

Singhi, A.D., Stelow, E.B., Mills, S.E. and Westra, W.H. Lymphoepithelial-like carcinoma of the oropharynx: a morphologic variant of HPV-related head and neck carcinoma. Am. J. Surg. Pathol. 2010 Jun; 34(6): 800-5.

Singhi, A.D. and Westra, W.H. Comparison of HPV in-situ hybridization and p16 immunohistochemistry in the detection of HPV-associated head and neck cancer based on a prospective clinical experience. Cancer. 2010 May 1; 116(9): 2166-73.

Lu, T., Jackson, M.W., Singhi, A.D., Kandel, E.S., Yang, M., Zhang, Y., Gudkov, A.V. and Stark, G.R. Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB. Proc. Natl. Acad. Sci. USA. 2009 Sep 22; 106(38), 16339-44.