Pathology Graduate Training Program
Cellular and Molecular Pathology (CMP) -
Faculty and Their Research Interests

  • Wendy M. Mars, PhD, Director
    - The role of hepatocyte growth factor (HGF) and the plasminogen activator system in tissue regeneration.
  • Alejandro Soto-Gutierrez, MD, PhD, Associate Director - Liver Regeneration, cell transplantation and organ engineering.
  • Stephen F. Badylak, DVM, PhD, MD
    - Tissue engineering and regenerative medicine
  • Yaacov Barak, PhD
    - Placenta and adipose tissue
  • Michael J. Becich, MD, PhD
    - Pathology informatics
  • Aaron W. Bell, PhD, Assistant Professor
    - Understanding the role of transcription factors in control and regulation of liver growth, regeneration, differentiation and carcinogenesis.
  • Sarah Berman, MD, PhD
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  • Timothy R. Billiar, PhD
    - Regulation and function of inducible nitric oxide synthase
  • Harry C. Blair, MD
    - Bone physiology and pathology
  • Bryan Brown, PhD
    - Inductive, Scaffold Based Regenerative Medicine, Host Innate Immune Interactions in Tissue Engineering and Regenerative Medicine.
  • Grant Carl Bullock, MD, PhD
    - Hematopathology, Molecular Hematopathology, Hematopoiesis, Iron Metabolism
  • J. Richard Chaillet, MD, PhD
    - Epigenetic inheritance in mammalian species
  • Stephen Y. Chan, MD, PhD
    - The molecular mechanisms of pulmonary vascular disease and pulmonary hypertension (PH)
  • Yuan Chang, MD
    - Viral oncogenesis
  • Charleen T. Chu, MD, PhD
    - Regulation of neurodegeneration and mitochondrial homeostasis; Parkinson's disease; ophthalmic pathology
  • Paula R. Clemens, MD
    - Pathogenesis of inherited muscular dystrophies, inflammatory myopathies, and cancer cachexia
  • Marie C. DeFrances, MD, PhD
    - PI3K signaling mechanisms in hepatocytes.
  • Anthony J. Demetris, MD
    - The role of inflammatory cytokines and growth factors in the development of cirrhosis & tolerance induction and chronic tissue rejection
  • Steven F. Dobrowolski, PhD
    - Intoxicating type inborn errors of metabolism: genetics, genomic assessment to identify genetic modifiers of the primary phenotype(s), and the role of epigenetic modification in disease presentation
  • H. Henry Dong, PhD
    - Insulin resistance to diabetic dyslipidemia and insulin replacement
  • Albert D. Donnenberg, PhD
    - Identification of therapeutic targets on cancer stem cells
  • Anette U. Duensing, MD
    - Gastrointestinal stromal tumors (GIST)
  • Andrew W. Duncan, PhD
    - Liver development, homeostasis and regeneration
  • Ira J. Fox, MD
    - Experimental therapies for liver disease
  • Mark T. Gladwin, MD
    - Pulmonary hypertension and pulmonary complications of sickle cell disease
  • Delphine Gomez, PhD
    - The functional role of epigenetic and transcriptional mechanisms in controlling key properties of vascular smooth muscle cells (SMC) including cell differentiation, lineage memory and plasticity in the context of major cardiovascular diseases including atherosclerosis.
  • Elena A. Goncharova, PhD
    - The molecular mechanisms regulating cellular energy metabolism, proliferation, motility and survival in the pathogenesis of pulmonary arterial hypertension (PAH) and pulmonary lymphangioleiomyomatosis (LAM).
  • Cynthia St. Hilaire, PhD
    - Arterial calcification due to deficiency of CD73 (ACDC)
  • Hun-Way Hwang, MD, PhD
    - mRNA regulation in both physiologic and disease scenarios with a special emphasis on 3-prime UTR-mediated regulation.
  • Jeff Isenberg, MD, MPH
    - Enhancing tissue blood flow, perfusion and wound healing, and stem from his background as a reconstructive microsurgeon.
  • Nahed Ismail, MD, MSc, PhD, D(ABMM), D(ABMLI)
    - Understanding the immune mechanisms involved in host defense against intracellular bacteria
  • John M. Kirkwood, MD
    - To develop improved therapy for inoperable advanced melanoma
  • Scott Kulich, MD, PhD
    - the interaction between oxidative neurotoxins and intracellular signal transduction
  • Robert Lafyatis, MD
    - Pathogenesis of systemic sclerosis, and its skin and pulmonary complications
  • Eric Lagasse, PharmD, PhD
    - Human stem/progenitor cells for liver diseases
  • Janet S. Lee, MD
    - Host susceptibility to lung injury and the role of phagocytes in the injury response
  • Youhua Liu, PhD
    - Dissecting cellular and molecular pathways leading to chronic renal fibrosis
  • Joseph Locker, MD, PhD
    - Control of hepatocyte cell proliferation
  • Anna E. Lokshin, PhD
    - Identification of cancer biomarkers for screening, diagnosis, prognosis, and disease monitoring of solid tumor cancers
  • Thomas Lozito, PhD
    - Understanding of divergent regenerative capabilities among vertebrates
  • Peter C. Lucas, MD, PhD
    - the role of an NF- κB signaling pathway that is controlled by the "CBM signalosome"
  • Jianhua Luo, MD, PhD
    - Genome and gene expression study of maligancies
  • Kacey G. Marra, PhD
    - Tissue engineering
  • George K. Michalopoulos, MD, PhD
    - Use the differentiated cells of the liver (hepatocytes) as models to understand the mechanisms that regulate growth of complex differentiated cells and whole organs.
  • Satdarshan P. Singh Monga, MD
    - Molecular mechanisms of liver growth and development, in health and disease.
  • Shanmugam Nagarajan, PhD
    - Auto-antibodies and preventing chronic inflammatory diseases
  • Kari Nejak-Bowen, PhD
    - The cellular and molecular basis of liver injury, regeneration, and cholestatic liver disease
  • Yuri E. Nikiforov, MD, PhD
    - Molecular mechanisms of radiation-induced carcinogenesis and chromosomal rearrangements in human cells and molecular basis of thyroid cancer.
  • Michael Oertel, PhD
    - hepatic cell transplantation.
  • Steffi Oesterreich, PhD
    - Endocrine resistance in breast cancer
  • Zoltan Oltvai, MD, PhD
    - Systems biology
  • Tim D. Oury, MD, PhD
    - Oxidative stress and innate immunity in pulmonary disease
  • Julie Phillippi, PhD
    -
  • Jon D. Piganelli, PhD
    - Oxidative stress and free radical generation
  • Iain Scott, PhD
    - Mitochondrial metabolism and bioenergetics
  • Melanie J Scott, MD, PhD
    - Innate immune responses after surgery, trauma, hemorrhagic shock and infection
  • Steven D. Shapiro, MD
    - Biological functions of matrix degrading proteinases
  • Alejandro Soto-Gutierrez, MD, PhD
    - Development of new technologies for organ replacement using regenerative medicine approaches
  • Donna Beer Stolz, PhD
    - Angiogenesis and vascular function
  • Urvashi Surti, PhD
    - The molecular cytogenetics of pregnancy loss and cancer.
  • Kenichi (Ken) Tamama, MD, PhD, FCAP
    - Cellular and molecular biology of mesenchymal stem cells
  • Angus W. Thomson, PhD, DSc
    - Regulatory immune cells, mTOR and transplant tolerance
  • Bryan W. Tillman, MD, PhD
    - Novel therapies for vascular graft failure resulting from graft stenosis
  • Rocky S. Tuan, MD
    - Biological activities underlying the development, growth, function, and health of skeletal tissues
  • Ivona Vasile-Pandrea, MD, PhD
    - SIV pathogenesis in progressive and nonprogressive hosts. Immune therapies for HIV infection
  • Nam Viet Vo, PhD
    - To understand the mechanisms of degeneration of matrix in the intervertebral discs and explore therapeutic strategies to minimize disc matrix loss
  • Yoram Vodovotz, PhD
    - Systems approaches to the biology of shock states, host-pathogen interactions, wound healing, and chronic inflammatory diseases
  • David Alan Vorp, PhD
    - Vascular biomechanics
  • Xiaosong Wang, MD, PhD
    - Integrative bioinformatics, cancer genetics, molecular cancer biology, and translational studies to identify genetic aberrations and appropriate cancer targets
  • Zhou Wang, PhD
    - Androgen action and the roles of androgens in benign and cancerous prostate growth
  • Alan Wells, MD, DMS
    - The role of cell migration in physiologic and pathologic conditions.
  • Sally E. Wenzel, MD
    - Pathobiology of asthma
  • Clayton A. Wiley, MD, PhD
    - Pathogenesis of neurodegenerative diseases and in particular on viral induced nervous system diseases.
  • Cary Wu, PhD
    - Cell adhesion: molecular mechanism and the roles in the pathogenesis of cancer and diabetic nephropathy.
  • Jian Yu, PhD
    - The molecular mechanisms of apoptosis in mammalian cells and its role in cancer therapy and carcinogenesis.
  • Reza Zarnegar, PhD
    - The analysis of hepatocyte growth factor (HGF) and HGF receptor (a protooncogene) function and their genetic regulation at the molecular level in vivo.