Pathology Graduate Training Program
Cellular and Molecular Pathology (CMP) -
Current Graduate Students

Name: Morgan Preziosi
Email: mep116@pitt.edu
Lab Phone: 412-648-8146
Mentor Name: Satdarshan (Paul) Monga

Education:
Undergraduate Degree: Biochemistry and Psychology
Undergraduate Institution: University of Rochester

Current Research Description:

We want to uncover the mechanisms that initiate liver regeneration. Using a partial hepatectomy (PHx) model, we hypothesize that an increase in portal pressure after PHx causes shear stress, which initiates sinusoidal endothelial cells to secrete Wnts. These Wnts may then activate hepatocyte ?-catenin signaling and proliferation, thus leading to regeneration.

Awards:

Angiopathy Training Program recipient

Graduate Honors:

Publications:

Shweta Tiwary, Morgan Preziosi, Paul Rothberg, Nathalie Zeitouni, Nancy Corson, Lei Xu. ERBB3 Is Required for Metastasis Formation of Melanoma Cells Regardless of Their Sensitivity to BRAFV600E Inhibitors, Oncogenesis, (2014) 3, e110; doi:10.1038/oncsis.2014.23

Abstracts:

Swetha Murthy, Jessica C. Page, Morgan E. Preziosi, Gabriela K. Popescu, Subunit Specific Impact of Lurcher Motif Residues on NMDA Receptor Gating, [Abstract]. Biophysical Journal, Volume 100, Issue 3, Supplement 1, 2 February 2011, Page 24a, ISSN 0006-3495, http://dx.doi.org/10.1016/j.bpj.2010.12.338. (http://www.sciencedirect.com/science/article/pii/S0006349510018412)

Presentations

2014, Attended the Federation of American Societies for Experimental Biology's Liver Biology conference and presented poster Sexual Dimorphic Response to Hepatic Iron Overload: A Wnt/β-catenin Perspective