Pathology Graduate Training Program
Cellular and Molecular Pathology (CMP) -
Alumni

Name: Yvonne Chao
Email: ylc3@pitt.edu
Lab Phone: 412-624-9366
Mentor Name: Alan Wells, MD, DMS

Undergraduate Education:
Undergraduate Degree: BS in Biology, 2004
Undergraduate Institution: Brown University

Academic Status: 2nd year
Thesis Advisor Alan Wells, MD, DMS

Research Project Information

I am investigating whether metastatic breast carcinoma cells require E-cadherin re-expression to integrate and to confer a survival advantage in the liver, a common site of breast cancer metastases.

Publications

Yeh JJ, Munson K, Chao Y, Peterson QP, MacRae CA, Peterson RT (2007). AML1-ETO Reprograms Hematopoietic Cell Fate in Zebrafish. Submitted.

De Paepe ME, Mao Q, Chao Y, Powell JL, Rubin LP, Sharma S. (2005). Hyperoxia-induced apoptosis and Fas/FasL expression in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. Oct;289(4):L647-59.

Zhou HW, Nussbaumer C, Chao Y, DeLong A. (2004). Disparate roles for the regulatory A subunit isoforms in Arabidopsis. Plant Cell. Mar;16(3):709-2

Abstracts:

DePaepe ME, Chao Y, Mao QF. (2004). Hyperoxia-induced apoptosis and apoptotic gene expression in lung epithelial cells. Developmental Biology of the Lung, Montreal, Canada, May.

Presentations:

Chao Y, Shepard CR, Wells, A. "E-cadherin as a chemotherapy resistance mechanism for breast cancer metastasis." Science 2008. Pittsburgh, PA. October 2008. (poster) Chao Y, Shepard CR, Wells, A. "E-cadherin as a chemotherapy resistance mechanism for breast cancer metastasis." DOD Breast Cancer Research Program Era of Hope meeting. Baltimore, MD. June 2008. (poster)

Chao Y, Shepard CR, Wells, A. "E-cadherin expression as a survival mechanism for breast cancer metastasis." ACLPS. Philiadelphia, PA. June 2008.

Chao Y, Donnenberg AD, Luketich JD, Zikos T, Gilles-Buck E, and Donnenberg VS. "Radiosensitivity of Tumorigenic Stem Cells in Human Cancer Samples". Science 2006. Pittsburgh, PA. October 2006

Chao Y, Donnenberg AD, Luketich JD, Zikos T, Gilles-Buck E, and Donnenberg VS. "Radiosensitivity of Tumorigenic Stem Cells in Human Cancer Samples". Department of Surgery Research Meeting. Pittsburgh, PA. August 31, 2006.

Honors:

Young Investigator Award, Academy of Clinical Physicians and Scientists, 2008
William Gaston Premium Scholarship in Biology, 2004