Pathology Graduate Training Program
Name: Vineet Agrawal
Cellular and Molecular Pathology (CMP) -
Lab Phone: 412-235-5162
Mentor Name: Stephen F. Badylak, MD
Undergraduate Degree: B.S.E., Biomedical Engineering, Electrical Engineering
Undergraduate Institution: Duke University
Research Project Information
There are approximately 1.7 million people in the United States currently living with an amputated limb, and it is projected that this number will increase to 3.6 million people by the year 2050. Identifying the processes underlying induction of limb growth could positively impact the quality of life of millions of people. The phenomenon of limb regrowth has been observed in lower species, such as the Xenopus and newt. However, a robust regenerative response in mammalian species is yet to be seen beyond the neonatal stage. Porcine extracellular matrix (ECM) derived scaffolds have successfully been used as a resorbable scaffold in over one million human patients for site specific, non-inflammatory repair of a variety of soft tissue. Our goal is to investigate methods by which to induce functional regrowth of limbs in adult mammalian species via use of ECM derived scaffolds.
Hwang WL, Agrawal V, Kaplan DM, Mian MK, Manson JE, Bissell A. "InnoWorks - A Portable, Interdisciplinary, University-Based Science and Engineering Program Emphasizing Experiential Learning for Underprivileged Middle School Students," ASEE, January 2006 (electronic edition).
Dahl JJ, Pinton GF, Palmeri ML, Agrawal V, Nightingale KR, Trahey GE. A parallel tracking method for acoustic radiation force impulse imaging. IEEE Trans UFFC 2007, 54(2): 301-312.
Trahey GE, Dahl JJ, Bouchard RR, Palmeri ML, Agrawal V. Parallel Tracking and other Methods for Real-time ARFI Imaging Systems. IEEE Ultrasonics Symposium 2006: 1005-1008.
Refereed Conference Proceedings:
Hwang WL, Agrawal V, Kaplan DM, Mian MK, Manson JE, Bissell A. "The InnoWorks Program: Boosting Scientific Literacy and Interest Among Underprivileged Middle School Students Using Experiential Learning Theory & College Volunteers," Western Carolina University Scholarship of Teaching and Learning Faire, Cullowhee, North Carolina, February 2006.
Agrawal V, Brennan EP, Reing J, Freytes DO, Badylak SF. Intestinal Progenitor Cells Preferentially Migrate and Proliferate in Response to Degradation Products of Small Intestinal Submucosa Extracellular Matrix Bioscaffolds, Regenerate International Conference, Toronto, Canada, June 2007.